An innovative radio-guided surgery technique for complete resection of tumors

被引：0
|
作者：
Russomando, A. [1 ,2 ,3 ]
Collamati, F. [1 ,2 ]
Bellini, F. [1 ,2 ]
Bocci, V. [2 ]
De Lucia, E. [4 ]
Faccini, R. [1 ,2 ]
Frallicciardi, P. M. [2 ,5 ]
Marafini, M. [2 ,5 ]
Mattei, I. [2 ,6 ]
Morganti, S. [2 ]
Patera, V. [2 ,7 ]
Piersanti, L. [2 ]
Pinci, D. [2 ]
Recchia, L. [2 ]
Senzacqua, M. [1 ,2 ]
Sarti, A. [7 ]
Sciubba, A. [2 ,7 ]
Camillocci, E. Solfaroli [3 ]
Voena, C. [1 ,2 ]
机构：
[1] Univ Roma La Sapienza, Dipartimento Fis, Rome, Italy
[2] INFN Sezione Roma, Rome, Italy
[3] Ist Italiano Tecnologia, Ctr Life Nano Sci Sapienza, Rome, Italy
[4] Laboratori Nazionali Frascati dell INFN, Frascati, Italy
[5] Museo Storico Fis Centro Studi Ric Fermi, Rome, Italy
[6] Univ RomaTre, Dept Fis, Rome, Italy
[7] Sapienza Univ Roma, Dept Sci Base Applicate Ingn, Rome, Italy
来源：
5TH YOUNG RESEARCHER MEETING | 2014年 / 566卷
关键词：
D O I：
10.1088/1742-6596/566/1/012020
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
Finding new ways to fight cancer is essential to increase the patients life expectancy. This paper reports the latest results of the project CHIRONE finalized to increase the potential of the Radio Guided Surgery through the use of beta(-) emitting radio-tracers and beta(-) probes. This innovation could overcome the present main limiting factor represented by a diffuse background due to the high penetration power of the gamma radiation used. We created a prototype of beta(-) probe and in this paper we report measures of photon efficiency, acquired with commercial photons sources. Then we estimated the signal and background rates in realistic cases of meningioma through a simulation. The device is able to detect residuals of 0.1 ml in 1 s with an administered activity less than 3 MBq/kg.
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页数：6
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