Gold Nanorod Translocation Through Nanopore: Experiment and Simulation

Nanopore has become one of the most promising applications in singe molecule detection. A detectable change of the ionic current generated by the translocation of nanoparticle enables the sensing of single molecule. In this work, we have studied the rigid gold nanorod as the sample that driven through the silicon nitride nanopore by the biased voltages. The nanorod passed through the nanopore results in a corresponding current change. Also a numerical model has been used to simulate the electric behavior as the nanorods passing through a nanopore. The electric potential and electric field distributions of the nanopore have been resolved in two dimensions by the COMSOL Multiphysics. Meanwhile, the fluid velocity field distribution of the electroosmotic flow (EOF) produced by electric double layers (EDL) within nanopore have also been figured out, as well as current simulation at different positions and times. Furthermore, the current values of nanorods with different sizes are also compared. These simulation results are helpful to understand the dynamic motion of nanoparticle through a nanoscale sized pores and channels.