Hepatitis B and C virus infection and risk of haematological malignancies

被引：6
|
作者：
Marrone, Aldo [1 ]
Ciotti, Marco [2 ]
Rinaldi, Luca [1 ]
Adinolfi, Luigi Elio [1 ]
Ghany, Marc [3 ]
机构：
[1] Univ Campania Luigi Vanvitelli, Dept Adv Med & Surg Sci, Naples, Italy
[2] Polyclin Tor Vergata Fdn, Lab Clin Microbiol & Virol, Rome, Italy
[3] NIDDK, Liver Dis Branch, Div Digest Dis & Nutr, NIH, Bethesda, MD 20892 USA
来源：
JOURNAL OF VIRAL HEPATITIS | 2020年 / 27卷 / 01期
关键词：
haematological malignancies; hepatitis B virus (HBV); hepatitis C virus (HCV); NON-HODGKIN-LYMPHOMA; CHRONIC LYMPHOCYTIC-LEUKEMIA; EPSTEIN-BARR-VIRUS; MIXED CRYOGLOBULINEMIA; MICRORNA EXPRESSION; HIGH PREVALENCE; HCV INFECTION; IMMUNOGLOBULIN GENE; ANTIVIRAL TREATMENT; MONONUCLEAR-CELLS;
D O I：
10.1111/jvh.13183
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are classified as oncogenic human viruses. Chronic HBV and HCV infections are associated with higher risk of haematological malignancy development. Direct and indirect oncogenic mechanisms have been demonstrated for both HBV and HCV in several studies. HCV and overt/occult HBV infections in patients with oncohaematological disease constitute an impediment and a threat during immunosuppressive chemotherapy treatment. We review the HBV and HCV oncogenic mechanisms and the impact and the safety of antiviral treatment in patients with haematological malignancies.
引用
收藏
页码：4 / 12
页数：9
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