The paradox of natural products as pharmaceuticals -: Experimental evidences of a mango stem bark extract

被引：43
|
作者：
Nunez-Selles, Alberto J. [1 ]
Delgado-Hernandez, Rene [1 ]
Garrido-Garrido, Gabino [1 ]
Garcia-Rivera, Dagmar [1 ]
Guevara-Garcia, Mariela [1 ]
Pardo-Andreu, Gilberto L. [1 ]
机构：
[1] Ctr Pharmaceut Chem, Havana 11600, Cuba
来源：
PHARMACOLOGICAL RESEARCH | 2007年 / 55卷 / 05期
关键词：
Mangifera indica; Vimang; natural products; anti oxidant; oxidative stress; monoceuticals; natureceuticals; health; quality of life;
D O I：
10.1016/j.phrs.2007.01.004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Recent findings regarding basic, pre-clinical and clinical studies on a mango stem bark extract (MSBE) developed in Cuba (Vimang) on an industrial scale are summarized. Ethnomedical studies, extract reproducibility, biological effects and clinical evaluations in terms of patient quality of life are described as experimental evidences to support the statement that natural products, even being a mixture of compounds, could be as effective as "monoceuticals" for medical uses. Discussion about the use of "monoceuticals" versus "natureceuticals" in health care and medicine is based on effectiveness and availability, taking Vimang as an example of a natural product with supported scientific evidence to be used as antioxidant, analgesic, anti-inflammatory and immunomodulator. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：351 / 358
页数：8
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