Metabolomic and secretomic approach to the resistance features of the fungus Aspergillus niger IOC 4687 to copper stress

被引：6

作者：

Cota de Almeida, Silas Perdigao ^{[1
]}

Rozas, Enrique Eduardo ^{[1
]}

Oller do Nascimento, Claudio Augusto ^{[1
]}

Dias, Meriellen ^{[1
]}

Mendes, Maria Anita ^{[1
]}

机构：

[1] Univ Sao Paulo, Dempster MS Lab, Chem Engn Dept, Polytech Sch, Rua Lago 250,Bloco B 3 Andar, BR-05508080 Sao Paulo, SP, Brazil

来源：

METALLOMICS | 2021年 / 13卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

OXIDATIVE STRESS; MANNITOL; EXPRESSION; MELANINS; GROWTH; METALS; ACID;

D O I：

10.1093/mtomcs/mfaa010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Metabolomic and secretomic analyses of Aspergillus niger IOC 4687 indicated the features of resistance of this strain to copper stress. To investigate the metabolites produced under oxidative stress conditions, gas chromatography-mass spectrometry analysis was performed. The secretome principal component analysis results showed that mannitol could be the main metabolite responsible for conferring resistance to the fungus, and gluconic acid is the possible cause of copper desorption because of its chelating ability. The meta-analysis of the metabolome of A. niger IOC 4687 indicated that a low concentration of sorbitol and ribonolactone during growth may be an indicator of oxidative stress.

引用

页数：8

共 29 条

[1] Response mechanism of mine-isolated fungus Aspergillus niger IOC 4687 to copper stress determined by proteomics
Dias, Meriellen
Jocelino Gomes de Lacerda, Jose Thalles
Cota de Almeida, Silas Perdigao
de Andrade, Lidiane Maria
Oller do Nascimento, Claudio Augusto
Rozas, Enrique Eduardo
Mendes, Maria Anita
METALLOMICS, 2019, 11 (09) : 1558 - 1566
[2] Autophagy is dispensable to overcome ER stress in the filamentous fungus Aspergillus niger
Burggraaf, Anne-Marie
Ram, Arthur F. J.
MICROBIOLOGYOPEN, 2016, 5 (04): : 647 - 658
[3] Biosorption of Copper using the Fungus Aspergillus niger Isolated from Contaminated Soil
Al-Sabri, Ahmed E.
Moslem, Mohamed A.
Al-Sohaibani, Saleh
Ameen, Fuad
JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2014, 8 : 173 - 177
[4] Structural Features of Sugars That Trigger or Support Conidial Germination in the Filamentous Fungus Aspergillus niger
Hayer, Kimran
Stratford, Malcolm
Archer, David B.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2013, 79 (22) : 6924 - 6931
[5] STUDIES ON BIOCORROSION OF STAINLESS STEEL AND COPPER IN CZAPEK DOX MEDIUM WITH ASPERGILLUS NIGER FILAMENTOUS FUNGUS
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Tudosie, Liana-Mihaiela
Cojocaru, Anca
Lingvay, Monika
Prioteasa, Paula
Visan, Teodor
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[6] Sorption Change in Electric Resistance of a Varnished Cambric Insulation by Exposure to the Microscopic Fungus Aspergillus niger
I. G. Kalinina
V. B. Ivanov
S. A. Semenov
V. V. Kazarin
O. A. Zhdanova
Russian Journal of Physical Chemistry B, 2020, 14 : 1014 - 1017
[7] Sorption Change in Electric Resistance of a Varnished Cambric Insulation by Exposure to the Microscopic Fungus Aspergillus niger
Kalinina, I. G.
Ivanov, V. B.
Semenov, S. A.
Kazarin, V. V.
Zhdanova, O. A.
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY B, 2020, 14 (06) : 1014 - 1017
[8] Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D
Li, Qiang
McNeil, Brian
Harvey, Linda M.
FREE RADICAL BIOLOGY AND MEDICINE, 2008, 44 (03) : 394 - 402
[9] The roles of the alternative NADH dehydrogenases during oxidative stress in cultures of the filamentous fungus Aspergillus niger
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Harvey, Linda M.
Mcneil, Brian
FUNGAL BIOLOGY, 2011, 115 (4-5) : 359 - 369
[10] EIS Study on Biocorrosion of Some Steels and Copper in Czapek Dox Medium Containing Aspergillus niger Fungus
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Prioteasa , Paula
Szatmari, Ilona
Radu, Elena
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