Residual Kidney Function: Implications in the Era of Personalized Medicine

被引：17
|
作者：
Shafi, Tariq [1 ,2 ]
Mullangi, Surekha [1 ]
Toth-Manikowski, Stephanie M. [1 ]
Hwang, Seungyoung [1 ]
Michels, Wieneke M. [3 ]
机构：
[1] Johns Hopkins Univ, Dept Med, Baltimore, MD USA
[2] Johns Hopkins Univ, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA
[3] Acad Med Ctr, Dept Med, Div Nephrol, Amsterdam, Netherlands
来源：
SEMINARS IN DIALYSIS | 2017年 / 30卷 / 03期
关键词：
NATIONAL COOPERATIVE DIALYSIS; GLOMERULAR-FILTRATION-RATE; RENAL-FUNCTION; HEMODIALYSIS-PATIENTS; KT/V-UREA; CLEARANCE; MORTALITY; FUROSEMIDE; DIURETICS; REMOVAL;
D O I：
10.1111/sdi.12587
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The association of residual kidney function (RKF) with improved outcomes in peritoneal dialysis and hemodialysis patients is now widely recognized. RKF provides substantial volume and solute clearance even after dialysis initiation. In particular, RKF provides clearance of non-urea solutes, many of which are potential uremic toxins and not effectively removed by conventional hemodialysis. The presence of RKF provides a distinct advantage to incident dialysis patients and is an opportunity for nephrologists to individualize dialysis treatments tailored to their patients' unique solute, volume, and quality of life needs. The benefits of RKF present the opportunity to personalize the management of uremia.
引用
收藏
页码：241 / 245
页数：5
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