Regression methods for cost-effectiveness analysis with censored data

被引:69
|
作者
Willan, AR
Lin, DY
Manca, A
机构
[1] Hosp Sick Children, Program Populat Hlth Sci, Res Inst, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Publ Hlth Sci, Toronto, ON, Canada
[3] Univ N Carolina, Dept Biostat, Chapel Hill, NC 27599 USA
[4] Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England
关键词
regression; censored data; cost-effectiveness; incremental net benefit; inverse probability weighting;
D O I
10.1002/sim.1794
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A system of seemingly unrelated regression equations is proposed for prognostic factor adjustment and subgroup analysis when comparing two groups in a cost-effectiveness analysis with censored data. Because of the induced dependent censoring on costs and quality-adjusted survival, inverse probability weighting is employed for parameter estimation. The method is illustrated with data from two recent examples using both survival time and quality-adjusted survival time as the measures of effectiveness. Copyright (C) 2004 John Wiley Sons, Ltd.
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页码:131 / 145
页数:15
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