3D-QSAR PHARMACOPHORE MODELING AND DOCKING STUDIES ON BENZIMIDAZOLE DERIVATIVES AS ACTIVATORS OF THE AMP-ACTIVATED PROTEIN KINASE (AMPK)

被引:0
|
作者
Sharma, Sugandha [1 ]
Balaramnavar, Vishal M. [1 ]
Saxena, Anil K. [1 ]
机构
[1] Cent Drug Res Inst, Med & Proc Chem Div, CSIR, Lucknow 226001, Uttar Pradesh, India
关键词
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:S124 / S125
页数:2
相关论文
共 50 条
  • [1] QSAR study and molecular docking of benzimidazole derivatives as potent activators of AMP-activated protein kinase
    Mrabti, Nidal Naceiri
    Elhallaoui, Menana
    JOURNAL OF TAIBAH UNIVERSITY FOR SCIENCE, 2017, 11 (01): : 18 - 39
  • [2] Pharmacophore modeling, 3D-QSAR and molecular docking studies of benzimidazole derivatives as potential FXR agonists
    Sindhu, Thangaraj
    Srinivasan, Pappu
    JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2014, 34 (04) : 241 - 253
  • [3] Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators
    Charton, Julie
    Girault-Mizzi, Sophie
    Debreu-Fontaine, Marie-Ange
    Foufelle, Fablenne
    Hainault, Isabelle
    Bizot-Espiard, Jean-Guy
    Caignard, Daniel-Henri
    Sergheraert, Christian
    BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (13) : 4490 - 4518
  • [4] Novel 4-Oxothienopyrimidinyl Propanoic Acid Derivatives as AMP-Activated Protein Kinase (AMPK) Activators
    Sasmal, Pradip K.
    Jaleel, Mahaboobi
    Rao, P. Tirumala
    Munikumar, M.
    Bhattacharya, Megha
    Kumar, Nutakki Ravi
    Neelima, Poondla.
    Rawoof, Khaji Abdul
    Rao, P. Narasimha
    Abbineni, Chandrasekhar
    Roshaiah, M.
    Sridhar, S.
    Kumar, Thammera Ranjith
    Vinu, Menon C. A.
    Potluri, Vijay
    Misra, Parimal
    Talwar, Rashmi
    Das, Saibal Kumar
    LETTERS IN DRUG DESIGN & DISCOVERY, 2014, 11 (06) : 778 - 785
  • [5] Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1
    Palani Kirubakaran
    Karthikeyan Muthusamy
    Kh. Dhanachandra Singh
    Selvaraman Nagamani
    Medicinal Chemistry Research, 2013, 22 : 3812 - 3822
  • [6] Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1
    Kirubakaran, Palani
    Muthusamy, Karthikeyan
    Singh, Kh Dhanachandra
    Nagamani, Selvaraman
    MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (08) : 3812 - 3822
  • [7] Combined Pharmacophore Modeling, Docking, and 3D-QSAR Studies of PLK1 Inhibitors
    Lu, Shuai
    Liu, Hai-Chun
    Chen, Ya-Dong
    Yuan, Hao-Liang
    Sun, Shan-Liang
    Gao, Yi-Ping
    Yang, Pei
    Zhang, Liang
    Lu, Tao
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2011, 12 (12): : 8713 - 8739
  • [8] Molecular Modeling Studies on Benzimidazole Carboxamide Derivatives as PARP-1 Inhibitors Using 3D-QSAR and Docking
    Zeng, Huahui
    Zhang, Huabei
    Jang, Fubin
    Zhao, Lingzhou
    Zhang, Jianyuan
    CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 78 (03) : 333 - 352
  • [9] Pharmacophore modeling and 3D-QSAR studies of 2,4-disubstituted pyrimidine derivatives as Janus kinase 3 inhibitors
    Agrawal, Neetu
    JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY, 2020, 19 (01):
  • [10] Discovery of 3,5-Dimethylpyridin-4(1H)-one Derivatives as Activators of AMP-Activated Protein Kinase (AMPK)
    Kuramoto, Kazuyuki
    Sawada, Yuki
    Ishibashi, Naoki
    Yamada, Tomohiro
    Nagashima, Takeyuki
    Shin, Takashi
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 68 (01) : 77 - 90