Recipient body size does not matter in pediatric liver transplantation

被引:9
|
作者
Chung, Patrick Ho Yu [1 ]
Chan, See Ching [2 ]
Mok, Vivian Way Kay [3 ]
Tam, Paul Kwong Hang [1 ]
Lo, Chung Mau [2 ]
机构
[1] Univ Hong Kong, Li Ka Shing Fac Med, Dept Surg, Div Paediat Surg, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, Li Ka Shing Fac Med, Dept Surg, Div Liver Transplantat, Hong Kong, Hong Kong, Peoples R China
[3] Univ Hong Kong, Li Ka Shing Fac Med, Dept Surg, Div Plast & Reconstruct Surg, Hong Kong, Hong Kong, Peoples R China
关键词
Liver transplantation; Pediatric; Living donor; Deceased donor; INFANTS YOUNGER; AGE; KILOGRAMS; LESS; COMPLICATIONS; BABIES;
D O I
10.1016/j.jpedsurg.2014.09.010
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background and purpose: It is controversial whether small size recipient is associated with adverse outcome in liver transplantation. This study aims to evaluate the outcomes of pediatric liver transplantation according to body weight of recipients. Methods: Liver transplant recipients (age < 18 years, from 1993 to 2011) were studied retrospectively. They were categorized according to the body size at the time of transplantation (A: < 6 kg; B: between 6 kg to 10 kg; C: > 10 kg). Results: A total of 113 patients (83 LDLTs and 30 DDLTs) were studied. Thirteen (11.5%) belonged to group A, 56 (49.6%) belonged to group B, and 44 (38.9%) belonged to group C. The best graft and patient survivals were found in group A (Figs. 1 and 2), and none of the patients required re-laparotomy for general surgical complications, while 32 patients (32%) in groups B and C did. Regarding transplant-related complications, although group A patients had the highest incidence of biliary tract complications (38.5%, n = 5), the incidence of vascular complications (hepatic artery: 7%, portal vein: 0%, hepatic vein: 0%) in this group was the lowest among the three groups. Conclusion: Outcomes of small-sized recipients are not inferior. Less technical-related vascular complications, which may lead to early graft loss, were observed. This could be patient-related (less advanced cirrhosis) or surgeon-related (additional attention paid). (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:1734 / 1737
页数:4
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