Cytotoxic T cell defects in x-linked Lymphoproliferative disease and reconstitution of abnormalities by SAP gene transfer

被引：0
|
作者：
Sharifi, R [1 ]
Buddle, J [1 ]
Gilmour, KC [1 ]
Kinnon, C [1 ]
Thrasher, AJ [1 ]
Gaspar, B [1 ]
机构：
[1] Inst Child Hlth, Mol Immunol Unit, London, England
来源：
MOLECULAR THERAPY | 2003年 / 7卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
1058
引用
收藏
页码：S408 / S408
页数：1
相关论文
共 50 条
  • [1] T Cell Gene Therapy Corrects Humoral and Cytotoxic Defects in X-Linked Lymphoproliferative Disease (XLP)
    Panchal, Neelam
    Hougton, Ben
    Diez, Begona
    Thrasher, Adrian J.
    Gaspar, H. Bobby
    Booth, Claire
    MOLECULAR THERAPY, 2017, 25 (05) : 31 - 32
  • [2] SAP mediates specific cytotoxic T-cell functions in X-linked lymphoproliferative disease
    Sharifi, R
    Sinclair, JC
    Gilmour, KC
    Arkwright, PD
    Kinnon, C
    Thrasher, AJ
    Gaspar, HB
    BLOOD, 2004, 103 (10) : 3821 - 3827
  • [3] Transfer of gene-corrected T cells corrects humoral and cytotoxic defects in patients with X-linked lymphoproliferative disease
    Panchal, Neelam
    Houghton, Ben
    Diez, Begona
    Ghosh, Sujal
    Ricciardelli, Ida
    Thrasher, Adrian J.
    Gaspar, H. Bobby
    Booth, Claire
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 142 (01) : 235 - +
  • [4] Development of T cell mediated gene therapy for correction of humoral and cytotoxic defects in X-linked lymphoproliferative disease (XLP)
    Panchal, Neelam
    Houghton, Benjamin
    Diez, Begona
    Thrasher, Adrian
    Gaspar, Bobby
    Booth, Claire
    HUMAN GENE THERAPY, 2017, 28 (08) : A10 - A11
  • [5] The X-linked lymphoproliferative disease gene product SAP associates with PIX and participates in T cell activation
    Wu, Jun
    JOURNAL OF IMMUNOLOGY, 2007, 178
  • [6] The X-linked lymphoproliferative disease gene product SAP is expressed in activated T and NK cells
    Nagy, N
    Mattsson, K
    Maeda, A
    Liu, AQ
    Székely, L
    Klein, E
    IMMUNOLOGY LETTERS, 2002, 82 (1-2) : 141 - 147
  • [7] SAP gene transfer restores cellular and humoral immune function in a murine model of X-linked lymphoproliferative disease
    Rivat, Christine
    Booth, Claire
    Alonso-Ferrero, Maria
    Blundell, Michael
    Sebire, Neil J.
    Thrasher, Adrian J.
    Gaspar, H. Bobby
    BLOOD, 2013, 121 (07) : 1073 - 1076
  • [8] Genomic organization and characterization of mouse SAP, the gene that is altered in X-linked lymphoproliferative disease
    Wu, CB
    Sayos, J
    Wang, NH
    Howie, D
    Coyle, A
    Terhorst, C
    IMMUNOGENETICS, 2000, 51 (10) : 805 - 815
  • [9] Genomic organization and characterization of mouse SAP, the gene that is altered in X-linked lymphoproliferative disease
    Chengbin Wu
    Joan Sayos
    Ninghai Wang
    Duncan Howie
    Anthony Coyle
    Cox Terhorst
    Immunogenetics, 2000, 51 : 805 - 815
  • [10] MAPPING THE GENE FOR X-LINKED LYMPHOPROLIFERATIVE DISEASE
    HECHT, F
    CANCER GENETICS AND CYTOGENETICS, 1990, 47 (02) : 271 - 272
12345