Cytotoxic steroidal saponins from Polygonatum zanlanscianense

被引：32
|
作者：
Jin, JM [1 ]
Zhang, YJ [1 ]
Li, HZ [1 ]
Yang, CR [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources, Kunming 650204, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 12期
关键词：
D O I：
10.1021/np049897u
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Four new steroidal saponins, polygonatosides A-D (1-4), were isolated from the rhizomes of Polygonatum zanlanscianense, together with six known spirostanols (5-10) and a known megastigmane glycoside (11). Their structures were elucidated on the basis of spectroscopic analysis and the results of acidic and enzymatic hydrolysis. The cytotoxic activities of 1-11 against HeLa cells are described.
引用
收藏
页码：1992 / 1995
页数：4
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