Breathe: Your Mitochondria Will Do the Rest ... If They Are Healthy!

被引：3
|
作者：
Viscomi, Carlo [1 ]
Zeviani, Massimo [1 ,2 ]
机构：
[1] MRC, Mitochondrial Biol Unit, Cambridge CB2 0XY, England
[2] Univ Padua, Dept Neurosci, Padua, Italy
来源：
CELL METABOLISM | 2019年 / 30卷 / 04期
关键词：
HYPOXIA;
D O I：
10.1016/j.cmet.2019.09.004
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Dysfunctions of the mitochondrial electron transport chain cause severe, currently untreatable, diseases in humans. A new study by Jain et al. (2019) reports increased oxygen levels in the brain of complex-I-deficient mice. Reducing the O-2 levels by hypoxia, carbon monoxide, or anemia, improved the clinical phenotype and prolonged the lifespan of the mouse model.
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页码：628 / 629
页数：2
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