Peri- and intra-operative management of the goat during acute surgical experimentation

被引：9
|
作者：
Flaherty, Devin C. [3 ,4 ]
Hoxha, Besim [4 ,5 ]
Nelson, Shirley [1 ]
Sun, Jie [3 ]
Gurji, Hunaid [3 ,4 ]
Simecka, Jerry W. [2 ]
Mallet, Robert T. [3 ,4 ,5 ]
Olivencia-Yurvati, Albert H. [3 ,4 ,5 ]
Daniels, Egeenee Q. [1 ]
机构：
[1] Univ N Texas, Hlth Sci Ctr, Dept Lab Anim Med, Ft Worth, TX 76107 USA
[2] Univ N Texas, Hlth Sci Ctr, Dept Mol Biol & Immunol, Ft Worth, TX USA
[3] Univ N Texas, Hlth Sci Ctr, Dept Integrat Physiol, Ft Worth, TX USA
[4] Univ N Texas, Hlth Sci Ctr, Dept Surg, Ft Worth, TX USA
[5] Univ N Texas, Hlth Sci Ctr, Cardiovasc Res Inst, Ft Worth, TX USA
来源：
LAB ANIMAL | 2010年 / 39卷 / 03期
关键词：
Q-FEVER; DIAZEPAM-KETAMINE; PULMONARY-EDEMA; SHEEP; GUIDELINES; OUTBREAK;
D O I：
10.1038/laban0310-80
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Goats are used as animal models for surgery and trauma research. The authors discuss appropriate methods for induction of anesthetics, intubation and surgical maintenance of the goat during acute experimentation. Risks imposed by the Q fever pathogen Coxiella burnetii are described, as well as measures that have proven effective in minimizing zoonotic transmission of this pathogen to laboratory personnel. With appropriate knowledge of its applications, peri- and intra-operative management and limitations, the goat is a suitable animal model for a variety of biomedical research applications.
引用
收藏
页码：80 / 85
页数：6
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