Vanadium complexes with polypyridyl ligands: Speciation, structure and potential medicinal activity

被引：15

作者：

Hernandez, Lino ^{[1
]}

Lorena Araujo, Mary ^{[2
]}

Madden, Waleska ^{[1
]}

Del Carpio, Edgar ^{[1
,3
]}

Lubes, Vito ^{[1
]}

Lubes, Giuseppe ^{[1
]}

机构：

[1] Univ Simon Bolivar USB, Lab Equilibrios Soluc, Apartado 89000, Caracas 1080, Venezuela

[2] Univ Cent Venezuela, Fac Ciencias, Ctr Equilibrios Soluc, Escuela Quim, Caracas, Venezuela

[3] Univ Cent Venezuela, Fac Farm, Escuela Dr Jemis Maria Bianco, Unidad Quim Med, Caracas, Venezuela

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 2022年 / 229卷

关键词：

Vanadium; Vanadium-based complexes; Polypyridyl ligands; Anticancer activity; Speciation studies; Cytotoxicity; AGENT VANADOCENE DICHLORIDE; OSTEOBLAST-LIKE CELLS; AMINO-ACIDS GLYCINE; 0.6 M NA(CL); OR-EQUAL-TO; DNA CLEAVAGE; V-51; NMR; SPECTROSCOPIC CHARACTERIZATION; OXIDOVANADIUM(IV) COMPLEXES; MULTICOMPONENT POLYANIONS;

D O I：

10.1016/j.jinorgbio.2022.111712

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review focuses on the interaction between the essential element-vanadium with 1,10-phenanthroline and polypyridyl ligands. It starts with a summary of the prior work on speciation studies for the binary systems vanadium-phenanthroline alongside several hydrolytic studies of the metal ion. It also includes a complete overview on the different X-ray structures known to date with discussions on the potential cytotoxic activity of several vanadium-polypyridyl complexes.

引用

页数：30

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