Synthesis of 3,3-disubstituted oxindoles by organoselenium-induced radical cyclizations of N-arylacrylamides

被引：10
|
作者：
Fu, Wei-jun [1 ]
Zhu, Mei [1 ]
Zou, Guang-long [2 ]
机构：
[1] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471022, Peoples R China
[2] Guizhou Minzu Univ, Sch Chem & Enviromental Sci, Guiyang 550025, Peoples R China
来源：
HETEROCYCLIC COMMUNICATIONS | 2015年 / 21卷 / 01期
基金：
中国国家自然科学基金;
关键词：
alkenes; cyclization; organoselenium; oxindole; radical cyclization; ACTIVATED ALKENES; FUNCTIONALIZATION;
D O I：
10.1515/hc-2014-0195
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and practical approach to oxindole derivatives via organoselenium-induced radical cyclizations of N-arylacrylamides has been developed. This method provides a convenient access to a variety of selenium-containing oxindoles in good to excellent yields under relatively mild reaction conditions. As one of its notable features, the radical process allows for the direct formation of a Se-C bond and the construction of a oxindole ring in one reaction.
引用
收藏
页码：9 / 12
页数：4
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