Obesity is a risk factor for many cancers. Maguire et al. (2021) found increased creatine synthesis by the adipocytes adjacent to breast cancers in obese mice. The creatine is transported into the cancer cells, producing larger tumors, possibly due to greater energy availability.
机构:
Thomas Jefferson Univ, Dept Pharmacol & Expt Therapeut, Philadelphia, PA 19107 USAThomas Jefferson Univ, Dept Pharmacol & Expt Therapeut, Philadelphia, PA 19107 USA
Blomain, Erik S.
Waldman, Scott A.
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Thomas Jefferson Univ, Dept Pharmacol & Expt Therapeut, Philadelphia, PA 19107 USAThomas Jefferson Univ, Dept Pharmacol & Expt Therapeut, Philadelphia, PA 19107 USA
机构:
Inst Gustave Roussy, Dept Med, Villejuif, FranceUniv Paris 06, Serv Histol Biol Tumorale, Hop Tenon, APHP,EA3499, Paris, France
Besse, Benjamin
Soria, Lean-Charles
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Inst Gustave Roussy, Dept Med, Villejuif, FranceUniv Paris 06, Serv Histol Biol Tumorale, Hop Tenon, APHP,EA3499, Paris, France
Soria, Lean-Charles
Bernaudin, Jean-Francois
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Univ Paris 06, Serv Histol Biol Tumorale, Hop Tenon, APHP,EA3499, Paris, FranceUniv Paris 06, Serv Histol Biol Tumorale, Hop Tenon, APHP,EA3499, Paris, France
Bernaudin, Jean-Francois
Callard, Patrice
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Univ Paris 06, Serv Anat Pathol, Hop Tenon, APHP,EA3499, Paris, FranceUniv Paris 06, Serv Histol Biol Tumorale, Hop Tenon, APHP,EA3499, Paris, France
机构:
Univ New South Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia
Univ Virginia, Dept Pharmacol, Charlottesville, VA 22908 USAUniv New South Wales, Sch Biotechnol & Biomol Sci, Sydney, NSW 2052, Australia
机构:
Penn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USAPenn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USA
Lin, Shengchen
Taylor, Matthew D.
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Penn State Univ, Dept Surg, Coll Med, Hershey, PA USAPenn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USA
Taylor, Matthew D.
Singh, Pankaj K.
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Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Eppley Inst Res Canc & Allied Dis, Omaha, NE USAPenn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USA
Singh, Pankaj K.
Yang, Shengyu
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Penn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USAPenn State Univ, Coll Med, Dept Cellular & Mol Physiol, Hershey, PA 17033 USA