Management of abdominal sepsis

Sepsis is still a major problem and accompanied by a high perioperative morbidity and mortality in surgical intensive care units. It is a clinical syndrome that complicates severe local abdominal infection ( peritonitis) and is characterized by systemic inflammation and widespread extraperitoneal systemic tissue injury, requiring multidisciplinary coordination of intensive care. Crucial is rapid diagnosis and an early goal-directed causal therapy of abdominal sepsis in terms of radical focus sanitation as well as aggressive systemic antibiotics. These standard therapy regimes are supplemented by additional therapeutic strategies depending on the severity score.