Immunotherapy plus gene therapy: a novel nanomedicine carrying the RB94 gene that suppresses tumor growth in non-small-cell lung cancer by inducing immunogenic cell death & modulating host immunity

被引:0
|
作者
Harford, Joe [1 ]
Doherty, Caroline [1 ]
Moghe, Manish [2 ]
Rait, Antonina [2 ]
Metallo, Steven [3 ]
Pirollo, Kathleen [2 ]
Chang, Esther [2 ]
Kim, Sang-Soo [1 ,3 ]
机构
[1] SynerGene Therapeut Inc, Potomac, MD USA
[2] Georgetown Univ, Med Ctr, Washington, DC 20007 USA
[3] Georgetown Univ, Washington, DC USA
来源
关键词
NANODELIVERY SYSTEM;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P631
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity
    Kim, Sang-Soo
    Doherty, Caroline
    Moghe, Manish
    Rait, Antonina
    Pirollo, Kathleen F.
    Harford, Joe B.
    Chang, Esther H.
    CANCERS, 2022, 14 (20)
  • [2] Crizotinib: A novel, targeted gene therapy for the treatment of non-small-cell lung cancer
    Patel, Kejal
    Abdelghany, Sam
    FORMULARY, 2011, 46 (11) : 460 - +
  • [3] TRIM14 IS A NOVEL TUMOR SUPPRESSOR GENE IN NON-SMALL-CELL LUNG CANCER
    Hai, Josephine
    Zhu, Chang Q.
    Tsao, Ming S.
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S1047 - S1048
  • [4] Synthesis and Application of a Novel Gene Delivery Vector for Non-Small-Cell Lung Cancer Therapy
    Yang, Yi
    Xue, Bingxin
    Shi, Kun
    Jia, Yanpeng
    Hao, Ying
    Xiao, Yao
    Qian, Zhiyong
    JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2019, 15 (03) : 431 - 442
  • [5] C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer
    Shi, Y.
    Chen, J.
    Li, Z.
    Zhang, Z.
    Yu, H.
    Sun, K.
    Wang, X.
    Song, X.
    Wang, Y.
    Zhen, Y.
    Yang, T.
    Lou, K.
    Zhang, Y.
    Zhang, G.
    Hu, Y.
    Ji, J.
    Hui, R.
    ONCOGENE, 2011, 30 (39) : 4107 - 4117
  • [6] C10ORF97 is a novel tumor-suppressor gene of non-small-cell lung cancer and a functional variant of this gene increases the risk of non-small-cell lung cancer
    Y Shi
    J Chen
    Z Li
    Z Zhang
    H Yu
    K Sun
    X Wang
    X Song
    Y Wang
    Y Zhen
    T Yang
    K Lou
    Y Zhang
    G Zhang
    Y Hu
    J Ji
    R Hui
    Oncogene, 2011, 30 : 4107 - 4117
  • [7] (-)-Guaiol triggers immunogenic cell death and inhibits tumor growth in non-small cell lung cancer
    Yang, Xiaohui
    Yang, Junling
    Gu, Xiaoxia
    Tao, Yuhua
    Ji, Hongjuan
    Miao, Xian
    Shen, Shuijie
    Zang, Haiyang
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2023, 478 (07) : 1611 - 1620
  • [8] (−)-Guaiol triggers immunogenic cell death and inhibits tumor growth in non-small cell lung cancer
    Xiaohui Yang
    Junling Yang
    Xiaoxia Gu
    Yuhua Tao
    Hongjuan Ji
    Xian Miao
    Shuijie Shen
    Haiyang Zang
    Molecular and Cellular Biochemistry, 2023, 478 : 1611 - 1620
  • [9] Targeted therapy for non-small-cell lung cancer: New insights into regulated cell death combined with immunotherapy
    Li, Shutong
    Wang, Aoxue
    Wu, Yongya
    He, Shengyuan
    Shuai, Wen
    Zhao, Min
    Zhu, Yumeng
    Hu, Xiuying
    Luo, Yubin
    Wang, Guan
    IMMUNOLOGICAL REVIEWS, 2024, 321 (01) : 300 - 334
  • [10] Tumor Treating Fields therapy could potentiate immunotherapy in non-small-cell lung cancer
    Fennell, Dean
    LANCET ONCOLOGY, 2023, 24 (09): : 946 - 947