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Clathrin-mediated endocytosis in budding yeast at a glance
被引:83
|作者:
Lu, Rebecca
[1
]
Drubin, David G.
[1
]
Sun, Yidi
[1
]
机构:
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, 229 Stanley Hall, Berkeley, CA 94720 USA
基金:
美国国家卫生研究院;
关键词:
Saccharomyces cerevisiae;
Actin;
Clathrin-mediated endocytosis;
Phospholipids;
Phosphorylation;
Ubiquitylation;
SERINE/THREONINE KINASE PRK1P;
CORTICAL ACTIN CYTOSKELETON;
SACCHAROMYCES-CEREVISIAE;
PROTEIN-KINASES;
PLASMA-MEMBRANE;
PHOSPHOREGULATION;
INTERNALIZATION;
ORGANIZATION;
ASSOCIATION;
MACHINERY;
D O I:
10.1242/jcs.182303
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
Clathrin-mediated endocytosis is an essential cellular process that involves the concerted assembly and disassembly of many different proteins at the plasma membrane. In yeast, live-cell imaging has shown that the spatiotemporal dynamics of these proteins is highly stereotypical. Recent work has focused on determining how the timing and functions of endocytic proteins are regulated. In this Cell Science at a Glance article and accompanying poster, we review our current knowledge of the timeline of endocytic site maturation and discuss recent works focusing on how phosphorylation, ubiquitylation and lipids regulate various aspects of the process.
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页码:1531 / 1536
页数:6
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