Issue: Nitric oxide (NO) is improbable as a conventional neurotransmitter: It is not an amine, amino acid, or peptide; it is not stored in synaptic vesicles or released by exocytosis; and it does not interact with specific receptor subtypes in neuronal membranes. However; NO is synthesized upon demand in the brain, diffuses to receptor sites within the enzyme guanylyl cyclase, and has neurotransmitter-like functions.
机构:
Fundacao Oswaldo Cruz, Programa Posgrad Hist Ciencias & Saude, BR-20240012 Rio De Janeiro, BrazilFundacao Oswaldo Cruz, Programa Posgrad Hist Ciencias & Saude, BR-20240012 Rio De Janeiro, Brazil
Candido da Silva, Andre Felipe
HISTORIA CIENCIAS SAUDE-MANGUINHOS,
2009,
16
(03):
: 827
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832