Sesquiterpene lactones from Artemisia mongolica

被引：12
|
作者：
Zhu, Ziwei [1 ,2 ,3 ]
Turak, Ablajan [1 ,2 ]
Aisa, Haji Akber [1 ,2 ]
机构：
[1] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Zone, Urumqi 830011, Peoples R China
[2] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plants, Urumqi 830011, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100039, Peoples R China
来源：
PHYTOCHEMISTRY | 2022年 / 199卷
基金：
中国国家自然科学基金; 对外科技合作项目（国际科技项目）;
关键词：
Artemisia mongolica; Asteraceae; Sesquiterpene lactones; Single-crystal X-ray analysis; Anti-inflammatory; Antitumor;
D O I：
10.1016/j.phytochem.2022.113158
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Twelve undescribed sesquiterpene lactones and seven known sesquiterpene lactones were isolated from the whole plant of Artemisia mongolica. Their structures were elucidated based on the interpretation of NMR, HRESIMS, and electronic circular dichroism (ECD) data. The absolute configurations of mongolicolide A (1), mongolicolide C (3), 1R, 3S-Dihydroxy-7S, 11R-germacra-4Z.9Z-dien-12, 6S-olide (5), indicumolide E (9), indicumolide F (10), and indicumolide G (11) were determined by single-crystal X-ray crystallography. The X-ray crystal structure of artabsinolide E (15) was reported for the first time. In addition, beibersteneolide-B (13) showed moderate anti-inflammatory activity and marked antitumor activity, artemyriantholide E (18) show moderate antitumor activity.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Sesquiterpene lactones from Artemisia inculta
    Marco, JA
    SanzCervera, JF
    GarciaLliso, V
    Guara, M
    VallesXirau, J
    PHYTOCHEMISTRY, 1997, 45 (04) : 751 - 754
  • [2] Sesquiterpene lactones from Artemisia lucentica
    Marco, JA
    SanzCervera, JF
    GarciaLliso, V
    Batlle, N
    PHYTOCHEMISTRY, 1997, 45 (04) : 755 - 763
  • [3] SESQUITERPENE LACTONES FROM ARTEMISIA SPECIES
    ALKHATHLAN, HZ
    MOUSA, AA
    ALHAZIMI, HMG
    JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 1992, 14 (02): : 151 - 165
  • [4] SESQUITERPENE LACTONES FROM ARTEMISIA SPECIES
    MARCO, JA
    SANZ, JF
    SANCENON, F
    RUSTAIYAN, A
    SABERI, M
    PHYTOCHEMISTRY, 1993, 32 (02) : 460 - 462
  • [5] Sesquiterpene lactones from Artemisia lerchiana
    Todorova, MN
    Krasteva, ML
    PHYTOCHEMISTRY, 1996, 42 (04) : 1231 - 1233
  • [6] Sesquiterpene Lactones from Artemisia capillaris*
    Feng, Jia
    Jin, Ying-Jin
    Jia, Jing-Jie
    Cao, Jin-Feng
    Wang, Yi-Ting
    Li, Xi-Feng
    CHEMISTRY OF NATURAL COMPOUNDS, 2017, 53 (05) : 978 - 979
  • [7] Sesquiterpene Lactones from Artemisia capillaris*
    Jia Feng
    Ying-Jin Jin
    Jing-Jie Jia
    Jin-Feng Cao
    Yi-Ting Wang
    Xi-Feng Li
    Chemistry of Natural Compounds, 2017, 53 : 978 - 979
  • [8] SESQUITERPENE LACTONES FROM ARTEMISIA-LUDOVICIANA
    JAKUPOVIC, J
    TAN, RX
    BOHLMANN, F
    BOLDT, PE
    JIA, ZJ
    PHYTOCHEMISTRY, 1991, 30 (05) : 1573 - 1577
  • [9] SESQUITERPENE LACTONES FROM ARTEMISIA-HALOPHILA
    ARKHIPOVA, LI
    KASYMOV, SZ
    SIDYAKIN, GP
    KHIMIYA PRIRODNYKH SOEDINENII, 1970, (04): : 480 - +
  • [10] SESQUITERPENE LACTONES FROM ARTEMISIA-ARGENTEA
    ELEMARY, NA
    MAKBOUL, MA
    HAMED, M
    PHYTOCHEMISTRY, 1987, 26 (01) : 314 - 315
12345