MRI of small human stroke shows reversible diffusion changes in subcortical gray matter

被引：14

作者：

Doege, CA ^{[1
]}

Kerskens, CM ^{[1
]}

Romero, BI ^{[1
]}

Brunecker, P ^{[1
]}

von Pannwitz, W ^{[1
]}

Junge-Hülsing, J ^{[1
]}

Müller, B ^{[1
]}

Villringer, A ^{[1
]}

机构：

[1] Humboldt Univ, Fak Med, Univ Klinikum Charite, Neurol Klin & Poliklin, D-10117 Berlin, Germany

来源：

NEUROREPORT | 2000年 / 11卷 / 09期

关键词：

apparent diffusion coefficient; cerebral ischemia; diffusion; human; magnetic resonance imaging; subcortical gray matter;

D O I：

10.1097/00001756-200006260-00043

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Six patients who had suffered small cerebral ischemia affecting subcortical gray matter were examined with diffusion weighted imaging (DWI) and T2-weighted imaging within the first 8 h, during the next 2 days and after 5-16 days. Areas of apparent diffusion coefficient (ADC) decreases were observed acutely and reached the maximum size during the subsequent 2 days. Noticeably, in all subjects, a large portion of the ADC lesion was reversible as judged from the lesion size on final T2 image. The regular reversibility of the ADC decreases in this setting may indicate a hitherto not understood pathophysiological process occurring in small ischemic stroke; NeuroReport 11:2021-2024 (C) 2000 Lippincott Williams & Wilkins.

引用

页码：2021 / 2024

页数：4

共 23 条

[1] Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging [J].

Baird, AE ;

Benfield, A ;

Schlaug, G ;

Siewert, B ;

Lovblad, KO ;

Edelman, RR ;

Warach, S .

ANNALS OF NEUROLOGY, 1997, 41 (05) :581-589

[2] SIMULTANEOUS RECORDING OF EEG, DC-POTENTIAL AND DIFFUSION-WEIGHTED NMR IMAGING DURING POTASSIUM-INDUCED CORTICAL SPREADING DEPRESSION IN RATS [J].

BUSCH, E ;

HOEHNBERLAGE, M ;

EIS, M ;

GYNGELL, ML ;

HOSSMANN, KA .

NMR IN BIOMEDICINE, 1995, 8 (02) :59-64

[3] Reperfusion after thrombolytic therapy of embolic stroke in the rat:: Magnetic resonance and biochemical imaging [J].

Busch, E ;

Krüger, K ;

Allegrini, PR ;

Kerskens, CM ;

Gyngell, ML ;

Hoehn-Berlage, M ;

Hossmann, KA .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 1998, 18 (04) :407-418

[4] TRANSIENT CELL DEPOLARIZATION AFTER PERMANENT MIDDLE CEREBRAL-ARTERY OCCLUSION - AN OBSERVATION BY DIFFUSION-WEIGHTED MRI AND LOCALIZED H-1-MRS [J].

GYNGELL, ML ;

BACK, T ;

HOEHNBERLAGE, M ;

KOHNO, K ;

HOSSMANN, KA .

MAGNETIC RESONANCE IN MEDICINE, 1994, 31 (03) :337-341

[5] Diffusion MRI in patients with transient ischemic attacks [J].

Kidwell, CS ;

Alger, JR ;

Di Salle, F ;

Starkman, S ;

Villablanca, P ;

Bentson, J ;

Saver, JL .

STROKE, 1999, 30 (06) :1174-1180

[6] Intra-arterial rtPA treatment of stroke assessed by diffusion- and perfusion-weighted MRI [J].

Lansberg, MG ;

Tong, DC ;

Norbash, AM ;

Yenari, MA ;

Moseley, ME .

STROKE, 1999, 30 (03) :678-680

[7] SPREADING WAVES OF DECREASED DIFFUSION-COEFFICIENT AFTER CORTICAL STIMULATION IN THE RAT-BRAIN [J].

LATOUR, LL ;

HASEGAWA, Y ;

FORMATO, JE ;

FISHER, M ;

SOTAK, CH .

MAGNETIC RESONANCE IN MEDICINE, 1994, 32 (02) :189-198

[8] MR IMAGING OF INTRAVOXEL INCOHERENT MOTIONS - APPLICATION TO DIFFUSION AND PERFUSION IN NEUROLOGIC DISORDERS [J].

LEBIHAN, D ;

BRETON, E ;

LALLEMAND, D ;

GRENIER, P ;

CABANIS, E ;

LAVALJEANTET, M .

RADIOLOGY, 1986, 161 (02) :401-407

[9] SEPARATION OF DIFFUSION AND PERFUSION IN INTRAVOXEL INCOHERENT MOTION MR IMAGING [J].

LEBIHAN, D ;

BRETON, E ;

LALLEMAND, D ;

AUBIN, ML ;

VIGNAUD, J ;

LAVALJEANTET, M .

RADIOLOGY, 1988, 168 (02) :497-505

[10] Clinical utility of diffusion-weighted magnetic resonance imaging in the assessment of ischemic stroke [J].

Lutsep, HL ;

Albers, GW ;

DeCrespigny, A ;

Kamat, GN ;

Marks, MP ;

Moseley, ME .

ANNALS OF NEUROLOGY, 1997, 41 (05) :574-580

← 1 2 3 →