Pathological examination of sentinel lymph node in breast cancer: Potential problems and possible solutions

被引:10
|
作者
Hoda, SA
Chiu, A
Resetkova, E
Harigopal, M
Hoda, RS
Osborne, MP
机构
[1] New York Presbyterian Hosp, Weill Cornell Med Ctr, Dept Pathol, New York, NY 10021 USA
[2] Cornell Univ, Weill Med Coll, Dept Pathol, New York, NY 10021 USA
[3] Cornell Univ, Weill Med Coll, Dept Surg, New York, NY 10021 USA
[4] Strang Weill Cornell Breast Ctr, New York, NY 10021 USA
[5] Med Univ S Carolina, Dept Pathol, Charleston, SC 29425 USA
关键词
breast carcinoma; lymph node; metastatic disease; micrometastatic disease; sentinel lymph node;
D O I
10.1002/jemt.10179
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Sentinel lymph node (SLN) biopsy has emerged during the last few years as a viable option for staging the axilla in the treatment of breast carcinoma. This procedure can potentially identify patients who would be helped by full axillary lymph node dissection (the SLN-positive cases), and those who would not (the SLN-negative cases). Review of the literature confirms the promise of SLN; however, the possible problems in the pathological handling of SLN, including the microscopic misinterpretation of benign structures and "spurious" immunohistochemical staining, need wider recognition.
引用
收藏
页码:85 / 91
页数:7
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