Signet Ring Cell Adenoma of the Thyroid: A Very Rare Entity

被引：7
|
作者：
Yalta, Tulin [1 ]
Elagoz, Sahende [3 ]
Uyar, Meral [1 ]
Topuz, Omer [2 ]
Ozer, Hatice [3 ]
Tuncer, Ersin [3 ]
机构：
[1] Sivas State Hosp, Dept Pathol, TR-58100 Sivas, Turkey
[2] Sivas State Hosp, Dept Gen Surg, TR-58100 Sivas, Turkey
[3] Cumhuriyet Univ, Dept Pathol, Sivas, Turkey
来源：
MEDICAL PRINCIPLES AND PRACTICE | 2010年 / 19卷 / 01期
关键词：
Signet ring cell adenoma; Thyroid lesion; Metastatic signet ring cell carcinoma; THYROGLOBULIN; ACCUMULATION;
D O I：
10.1159/000252840
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objectives: To report a case of signet ring cell adenoma of the thyroid which is an extremely rare thyroid lesion. Clinical Presentation and Intervention: A 25-year-old female patient presented with a goiter and dysphagia that had been present for the last 1 year before admission. Physical examination revealed a palpable solitary nodule in the right lobe of the thyroid. The ultrasonogram demonstrated multiple nodules among which the most remarkable one was 15 ! 24 mm in size, in the right lobe of the thyroid. After surgical excision, the lesion was found to be consistent with signet ring cell adenoma characterized by the presence of round to oval signet ring cells with large cytoplasmic vacuoles and hyperchromatic eccentric nuclei. Intracytoplasmic thyroglobulin, periodic acid-Schiff (PAS) with and without diastase and combined Alcian-blue-PAS were all positive. Conclusions: Pathologists should keep this rare primary tumor of the thyroid in mind when examining thyroid lesions and should not confound it with metastatic signet ring cell carcinoma of the thyroid. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码：76 / 78
页数：3
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