Assessing the landscape of selfish de novo mutations in human testes

被引:0
|
作者
Maher, G. J. [1 ]
Ralph, H. K. [1 ]
Ding, Z. [1 ]
Koelling, N. [1 ]
Mlcochova, H. [1 ]
Giannoulatou, E. [1 ]
Dhami, P. [2 ]
McVean, G. [1 ]
Wilkie, A. O. M. [1 ]
Goriely, A. [1 ]
机构
[1] Univ Oxford, Oxford, England
[2] UCL, London, England
基金
英国惠康基金;
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
C13.4
引用
收藏
页码:825 / 825
页数:1
相关论文
共 50 条
  • [1] Visualizing the origins of selfish de novo mutations in individual seminiferous tubules of human testes
    Maher, Geoffrey J.
    McGowan, Simon J.
    Giannoulatou, Eleni
    Verrill, Clare
    Goriely, Anne
    Wilkie, Andrew O. M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (09) : 2454 - 2459
  • [2] Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes
    Maher, Geoffrey J.
    Ralph, Hannah K.
    Ding, Zhihao
    Koelling, Nils
    Mlcochova, Hana
    Giannoulatou, Eleni
    Dhami, Pawan
    Paul, Dirk S.
    Stricker, Stefan H.
    Beck, Stephan
    McVean, Gilean
    Wilkie, Andrew O. M.
    Goriely, Anne
    GENOME RESEARCH, 2018, 28 (12) : 1779 - 1790
  • [3] DE NOVO SYNTHESIS OF STEROIDS BY TESTES OF HUMAN FOETUS AT MIDGESTATION
    MATHUR, RS
    WIQVIST, N
    DICZFALU.E
    ACTA ENDOCRINOLOGICA, 1971, : 135 - &
  • [4] De novo mutations in human genetic disease
    Veltman J.A.
    Brunner H.G.
    Nature Reviews Genetics, 2012, 13 (8) : 565 - 575
  • [5] Bad bones, absent smell, selfish testes: The pleiotropic consequences of human FGF receptor mutations
    Wilkie, AOM
    CYTOKINE & GROWTH FACTOR REVIEWS, 2005, 16 (02) : 187 - 203
  • [6] THE EMERGING LANDSCAPE OF SCHIZOPHRENIA RISK CONFERRED BY DE NOVO CODING MUTATIONS
    Howrtgan, Daniel
    Neale, Benjamin
    Samocha, Kaitlin
    Moran, Jennifer
    Chambert, Kimberly
    Rose, Samuel
    Fromer, Menachem
    Chandler, Sharon
    Laird, Nan
    Hwu, Hai-Gwo
    Chen, Wei J.
    Faraone, Stephen
    Glatt, Stephen
    Tsuang, Ming
    McCarroll, Steven
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2017, 27 : S346 - S347
  • [7] De novo mutations, genetic mosaicism and human disease
    Mohiuddin, Mohiuddin
    Kooy, R. Frank
    Pearson, Christopher E.
    FRONTIERS IN GENETICS, 2022, 13
  • [8] Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline
    Giannoulatou, Eleni
    McVean, Gilean
    Taylor, Indira B.
    McGowan, Simon J.
    Maher, Geoffrey J.
    Iqbal, Zamin
    Pfeifer, Susanne P.
    Turner, Isaac
    Wright, Emma M. M. Burkitt
    Shorto, Jennifer
    Itani, Aysha
    Turner, Karen
    Gregory, Lorna
    Buck, David
    Rajpert-De Meyts, Ewa
    Looijenga, Leendert H. J.
    Kerr, Bronwyn
    Wilkie, Andrew O. M.
    Goriely, Anne
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (50) : 20152 - 20157
  • [9] De Novo Mutations Reflect Development and Aging of the Human Germline
    Goldmann, J. M.
    Veltman, J. A.
    Gilissen, C.
    TRENDS IN GENETICS, 2019, 35 (11) : 828 - 839
  • [10] De novo mutations in epilepsy
    Saitsu, Hirotomo
    Matsumoto, Naomichi
    DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2011, 53 (09): : 806 - 807