A systematic study of the influence of higher-frequency ultrasonics on bond strength and the bondability of a variety of standard and advanced substrate/metallization combinations is reported The studies were carried out using two essentially identical thermosonic ball bonding machines, one bonding at nominally 60 kHz and the other at 100 kHz. Key to the study was the ability to make the bonding experiments as controlled, repeatable, and independent of all variables (except frequency) as possible. Control techniques included setting the electronic flame-off to produce consistently sized free-air balls; monitoring the ultrasonic voltage and current waveforms; and picking force, dwell, energy, and substrate heat settings that would allow strong bonds to be formed at both frequencies. Wirebonds (ball bonds) were evaluated primarily by the ball bond shear test. Statistical methods determined whether the differences in the means and variances between comparable samples sets (one bonded at 60 kHz and the other bonded at 100 kHz) were significant. Results indicate that significant differences exist between bonding at nominally 60 kHz and bonding at 100 kHz. In particular, we describe effects associated with (1) the ball shear strength before and after thermal aging (temperatures up to 200 degreesC) for both. 60-kHz and 100-kHz bonds, (2) the influence of substrate-metallizations combinations on the geometry and strength of the bonds at the different frequencies, and (3) the sensitivity and control of the overall bonding processes.