An ultrasensitive electrochemical "turn-on" label-free biosensor for Hg2+ with AuNP-functionalized reporter DNA as a signal amplifier

被引：114
|
作者：
Kong, Rong-Mei [1 ]
Zhang, Xiao-Bing [1 ]
Zhang, Liang-Liang [1 ]
Jin, Xiao-Yong [1 ]
Huan, Shuang-Yan [1 ]
Shen, Guo-Li [1 ]
Yu, Ru-Qin [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2009年 / 37期
基金：
中国国家自然科学基金;
关键词：
HIGHLY SENSITIVE DETECTION; MERR FAMILY PROTEINS; BIO-BAR CODES; GOLD NANOPARTICLES; AQUEOUS-SOLUTION; SELECTIVE DETECTION; MERCURIC ION; COLORIMETRIC DETECTION; FLUORESCENT SENSOR; OPTICAL-DETECTION;
D O I：
10.1039/b911163h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly selective electrochemical biosensor for the ultrasensitive detection of Hg2+ in aqueous solution has been developed based on the strong and specific binding of Hg2+ by two DNA thymine bases (T-Hg2+ -T) and the use of AuNP-functionalized reporter DNA to achieve signal amplification.
引用
收藏
页码：5633 / 5635
页数：3
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