Porphyrin-based Pt/Pd-containing metallopolymers: Synthesis, characterization, optical property and potential application in bioimaging

In this work, we report two metallopolymers (Pt-P and Pd-P) through coupling of Pt-II or Pd-II porphyrin with fluorene derivatives. The structure and photophysical properties of these two metallpolymers were fully characterized, which indicate that these two metallopolymers are of good capability for bioimaging of cancer cells. Hence, nanoprobes based on Pt-P and Pd-P for bioimaging of HeLa cancer cells were explored. The biological experimental results show that Pt-P NPs exhibit good biocompatibility and specificity to HeLa cancer cells due to its favorable NP size. (C) 2017 Elsevier B.V. All rights reserved.