Flow Cytometry in the Diagnosis of Canine T-Cell Lymphoma

被引：16
|
作者：
Comazzi, Stefano [1 ]
Riondato, Fulvio [2 ]
机构：
[1] Univ Milan, Dipartimento Med Vet, Lodi, Italy
[2] Univ Torino, Dipartimento Sci Vet, Grugliasco, Italy
来源：
FRONTIERS IN VETERINARY SCIENCE | 2021年 / 8卷
关键词：
dog; lymphoma; T-cell; flow cytometry; diagnosis; prognosis; BONE-MARROW INFILTRATION; PROGNOSTIC-SIGNIFICANCE; ZONE LYMPHOMA; B-CELL; MALIGNANT-LYMPHOMAS; DOGS; SUBTYPES; GRADE; CLASSIFICATION; POPULATION;
D O I：
10.3389/fvets.2021.600963
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
T cell lymphoma (TCL) is a heterogenous group of lymphoid malignancies representing about 30-40% of all canine lymphomas and often harboring a very aggressive behavior. WHO classification identifies the majority of TCLs as peripheral TCL, but other subtypes with peculiar presentation and outcome have been recognized. This review aims to explore the use of flow cytometry for refining the diagnosis of canine TCL, putting a particular emphasis on the identification of some peculiar immunotypes, such as T zone lymphoma; on the investigation of putative prognostic markers; and on the evaluation of lymphoma stage and of the minimal residual disease.
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页数：8
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