Mucin5AC/β-catenin Axis Bolsters c-Myc Driven Glutaminolysis to Suppress Gemcitabine Efficacy in Pancreatic Cancer

被引：0
|
作者：
Ganguly, K. [1 ]
Bhatia, R. [1 ]
Kisling, A. [1 ]
Vengoji, R. [1 ]
Rauth, S. [1 ]
Kaur, S. [1 ]
Krishna, S. R. [1 ]
Kumar, S. [1 ]
Batra, S. K. [1 ]
机构：
[1] Univ Nebraska Med Ctr, Dept Biochem & Mol Biol, Omaha, NE USA
来源：
PANCREAS | 2020年 / 49卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1409 / 1409
页数：1
相关论文
共 47 条
  • [1] Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance
    Ganguly, Koelina
    Bhatia, Rakesh
    Rauth, Sanchita
    Kisling, Andrew
    Atri, Pranita
    Thompson, Christopher
    Vengoji, Raghupathy
    Krishn, Shiv Ram
    Shinde, Dhananjay
    Thomas, Vinai
    Kaur, Sukhwinder
    Mallya, Kavita
    Cox, Jesse L.
    Kumar, Sushil
    Batra, Surinder K.
    GASTROENTEROLOGY, 2022, 162 (01) : 253 - +
  • [2] Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer
    Kang, Hyeon Woong
    Kim, Ju Hyun
    Lee, Da Eun
    Lee, Yun Sun
    Kim, Myeong Jin
    Kim, Hyung Sun
    Fang, Sungsoon
    Lee, Bo Eun
    Lee, Kyung Jin
    Yoo, Jongman
    Kim, Hyo Jung
    Park, Joon Seong
    CANCER BIOLOGY & THERAPY, 2023, 24 (01)
  • [3] c-Myc-PD-L1 Axis Sustained Gemcitabine-Resistance in Pancreatic Cancer
    Yao, Jingjing
    Huang, Min
    Shen, Qinghong
    Ding, Ming
    Yu, Shaofang
    Guo, Yajuan
    Lin, Yuefang
    Zheng, Yaqiu
    Chen, Wenbo
    Yan, Wenxin
    Liu, Zhongqiu
    Wang, Dawei
    Hu, Ming
    Lu, Linlin
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [4] Downregulation of MAL2 inhibits breast cancer progression through regulating β-catenin/c-Myc axis
    An, Lijun
    Gong, Huiyuan
    Yu, Xiaojing
    Zhang, Wangming
    Liu, Xiaohua
    Yang, Xiaomin
    Shu, Liping
    Liu, Jielin
    Yang, Liuqi
    CANCER CELL INTERNATIONAL, 2023, 23 (01)
  • [5] circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling
    Cai, Juan
    Chen, Zhiqiang
    Wang, Jinguo
    Wang, Junfeng
    Chen, Xianjun
    Liang, Linhu
    Huang, Min
    Zhang, Zhengrong
    Zuo, Xueliang
    CELL DEATH & DISEASE, 2019, 10 (8)
  • [6] Downregulation of MAL2 inhibits breast cancer progression through regulating β-catenin/c-Myc axis
    Lijun An
    Huiyuan Gong
    Xiaojing Yu
    Wangming Zhang
    Xiaohua Liu
    Xiaomin Yang
    Liping Shu
    Jielin Liu
    Liuqi Yang
    Cancer Cell International, 23
  • [7] circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling
    Juan Cai
    Zhiqiang Chen
    Jinguo Wang
    Junfeng Wang
    Xianjun Chen
    Linhu Liang
    Min Huang
    Zhengrong Zhang
    Xueliang Zuo
    Cell Death & Disease, 10
  • [8] The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer
    Tian-Lin He
    Yi-Jie Zhang
    Hui Jiang
    Xiao-hui Li
    Hai Zhu
    Kai-Lian Zheng
    Medical Oncology, 2015, 32
  • [9] Cinobufotalin regulates the USP36/c-Myc axis to suppress malignant of colon cancer cells in vitro and in vivo
    Hu, Yongjun
    Luo, Ming
    AGING-US, 2024, 16 (06): : 5526 - 5544
  • [10] Gel Forming Mucin MUC5AC Employs Multimodal Mechanism(s) to Augment Gemcitabine Resistance in Pancreatic Cancer
    Ganguly, K.
    Krishn, S. R.
    Jahan, R.
    Hayashi, C.
    Lu, Y.
    Huang, X.
    Lu, Y.
    Rachagani, S.
    Batra, S. K.
    Kaur, S.
    PANCREAS, 2017, 46 (10) : 1401 - 1401
12345