Uniformity of Offsprings from Uniform and Non-Uniform Parents

被引:0
|
作者
Gomes, M. Ivette [1 ]
Pestana, Dinis [1 ]
Sequeira, Fernando [1 ]
Mendonca, Sandra [2 ]
Velosa, Silvio [2 ]
机构
[1] Univ Lisbon, Fac Ciencias DEIO, CEAUL, Bloco C6,Piso 4,Campo Grande, P-1749016 Lisbon, Portugal
[2] Univ Madeira DME, CEAUL, P-9000390 Funchal, Portugal
关键词
Order statistics; combined p-values; uniform distribution; probability integral transformation; meta-analysis; SPACINGS;
D O I
暂无
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Combining independent tests using reported p-values, which under Ho are observations from a standard uniform random variable, is usually done in meta-analysis using either the distributional theory of order statistics from the uniform distribution, or using -2 Sigma(n)(k=1) ln P-k (sic) chi(2)(2n), or alternatively combining the normal scores z(k) := Phi(-1)(p(k)). However the number of p-values available is in general very small, and it would seem reasonable to generate extra "pseudo-p-values" in order to improve power, exploiting the rich theory of order statistics and spacings of uniform and e,exponential samples. Publication bias, an important concern in meta-analytical syntheses, is also discussed, namely the extra difficulty of considering the sample of available p-values as upper-censored. As publication bias favours reporting of moderate p-values (tipicaly smaller than 0.05), we investigate the proportion of "combined" rejections of uniformity when the primary set of p-values copies in fact from an alternative parent popalations which has higher probability than a uniform parent of generating small values. We present evidence that this fake augmentation of samples doesn't in fact improve results.
引用
收藏
页码:243 / +
页数:2
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