Real-time imaging of T-cell development

被引：9
|
作者：
Bousso, P [1 ]
机构：
[1] Inst Pasteur, Dept Immunol, INSERM, U277, F-75015 Paris, France
来源：
CURRENT OPINION IN IMMUNOLOGY | 2004年 / 16卷 / 04期
关键词：
D O I：
10.1016/j.coi.2004.05.015
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The cellular and molecular dynamics underlying intrathymic T-cell development are still poorly understood. Dynamic imaging techniques offer new opportunities for dissecting the complex journey of developing T cells in the thymus. In particular, two-photon laser scanning microscopy has recently demonstrated great promise in tracking lymphocyte behavior in tissue environments. Resolving thymocyte behavior at the single-cell level should help to clarify the mode of trafficking in the thymus and identify the spatio-temporal aspects of thymic selection events.
引用
收藏
页码：400 / 405
页数：6
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