An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer

被引：180

作者：

Burnett-Hartman, Andrea N. ^{[1
]}

Lee, Jeffrey K. ^{[2
,3
]}

Demb, Joshua ^{[4
]}

Gupta, Samir ^{[4
,5
]}

机构：

[1] Kaiser Permanente Colorado, Inst Hlth Res, 2550 S Parker Rd,Suite 200, Aurora, CO 80014 USA

[2] Kaiser Permanente Northern Calif, Div Res, San Francisco, CA USA

[3] Kaiser Permanente San Francisco Med Ctr, Dept Gastroenterol, San Francisco, CA USA

[4] Univ Calif San Diego, Dept Internal Med, Div Gastroenterol, La Jolla, CA 92093 USA

[5] VA San Diego Healthcare Syst, 3350 La Jolla Village Dr,MC 11D, San Diego, CA 92160 USA

来源：

GASTROENTEROLOGY | 2021年 / 160卷 / 04期

关键词：

Early-Onset Colorectal Cancer; Epidemiology; Red Flags;

D O I：

10.1053/j.gastro.2020.12.068

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Rising trends in the incidence and mortality of early-onset colorectal cancer (CRC) in those who are younger than 50 years have been well established. These trends have spurred intense investigation focused on elucidating the epidemiology and characteristics of early-onset CRC, as well as on identifying strategies for early detection and prevention. In this review, we provide a contemporary update on early-onset CRC with a particular focus on epidemiology, molecular characterization, red flag signs and symptoms, and screening for early-onset CRC.

引用

页码：1041 / 1049

页数：9

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