Inhibition of insulin receptor dephosphorylation mediated through IRS-1.

被引：0
|
作者：
Solow, BT [1 ]
Harada, S [1 ]
Smith, JA [1 ]
Smith, RM [1 ]
White, MF [1 ]
Jarett, L [1 ]
机构：
[1] UNIV PENN,SCH MED,DEPT PATHOL & LAB MED,PHILADELPHIA,PA 19104
来源：
MOLECULAR BIOLOGY OF THE CELL | 1997年 / 8卷
关键词：
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：745 / 745
页数：1
相关论文
共 50 条
  • [1] Protein kinase C mediates hyperglycemia induced insulin resistance through serine phosphorylation of IRS-1.
    Busch, AK
    Castan, I
    Degerman, E
    Tornqvist, H
    Mosthaf, L
    DIABETOLOGIA, 1998, 41 : A10 - A10
  • [2] IRS-1-mediated inhibition of insulin receptor signaling in TNF-alpha-induced insulin resistance
    Hotamisligil, GS
    Peraldi, P
    White, MF
    Spiegelman, BM
    DIABETES, 1996, 45 : 311 - 311
  • [3] IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance
    Hotamisligil, G.S.
    Peraldi, P.
    Budavari, A.
    Ellis, R.
    White, M.F.
    Spiegelman, B.M.
    Science, 1996, 271 (5249):
  • [4] IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    Hotamisligil, GS
    Peraldi, P
    Budavari, A
    Ellis, R
    White, MF
    Spiegelman, BM
    SCIENCE, 1996, 271 (5249) : 665 - 668
  • [5] Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling
    Tsuruzoe, K
    Emkey, R
    Kriauciunas, KM
    Ueki, K
    Kahn, CR
    MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (01) : 26 - 38
  • [6] Oxygen tension regulates the stability of insulin receptor substrate-1 (IRS-1) through caspase-mediated cleavage
    Kang, Sung Gyun
    Brown, Alexandra L.
    Chung, Jay H.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (09) : 6090 - 6097
  • [7] SH2B1 directly enhances insulin action by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of IRS proteins
    Morris, David
    Cho, Kae Won
    Zhou, Yingjiang
    Rui, Liangyou
    DIABETES, 2008, 57 : A383 - A383
  • [8] Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice
    Gonzalez-Rodriguez, Agueda
    Mas Gutierrez, Jose A.
    Sanz-Gonzalez, Silvia
    Ros, Manuel
    Burks, Deborah J.
    Valverde, Angela M.
    DIABETES, 2010, 59 (03) : 588 - 599
  • [9] Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice
    Dominici, FP
    Hauck, S
    Argentino, DP
    Bartke, A
    Turyn, D
    JOURNAL OF ENDOCRINOLOGY, 2002, 173 (01) : 81 - 94
  • [10] High-resolution structure of the tandem PH and PTB domains of IRS-1.
    DhePaganon, S
    Nolte, R
    Eck, M
    Shoelson, S
    DIABETES, 1997, 46 : 314 - 314
12345