Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes

被引：6
|
作者：
Li, Xiaojuan [1 ,2 ]
Zhang, Qiang [1 ,2 ]
Zhang, Weigang [1 ,2 ]
Ma, Jinzhu [3 ]
Wang, Yi [1 ,2 ]
Pan, Yi [1 ,2 ]
机构：
[1] Nanjing Univ, State Key Lab Coordinat Chem, Jiangsu Key Lab Adv Organ Mat, Sch Chem & Chem Engn, Nanjing 210023, Peoples R China
[2] Nanjing Univ, Collaborat Innovat Ctr Adv Microstruct, Sch Chem & Chem Engn, Nanjing 210023, Peoples R China
[3] Wannan Med Coll, Sch Pharm, Wuhu 241002, Peoples R China
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 17卷
基金：
中国国家自然科学基金;
关键词：
alkenes; difunctionalization; metal-free; photoredox; trifluoromethylthiolation; SILVER(I) TRIFLUOROMETHANETHIOLATE; SUBSTITUENT CONSTANTS; CHEMISTRY; FLUORINE; STYRENES;
D O I：
10.3762/bjoc.17.49
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The difunctionalization of alkenes involving a trifluoromethylthio group (SCF3) for the conversion of versatile and readily available olefins into structurally more complex molecules has been successfully studied. However, the disproportionate dithiolation of alkenes is unknown. Herein, a transition-metal-free protocol is presented for the vicinal trifluoromethylthio-thiolation of unactivated alkenes via a radical process under mild conditions with a broad substrate scope and excellent tolerance.
引用
收藏
页码：551 / 557
页数：7
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