A rare cause of a cholestatic jaundice in a North African teenager

被引：4

作者：

Schreiner, Philipp ^{[1
]}

Stieger, Bruno ^{[2
]}

McLin, Valerie ^{[3
]}

Rougemont, Anne-Laure ^{[4
]}

Keitel, Verena ^{[5
]}

Droege, Carola ^{[5
]}

Mullhaupt, Beat ^{[1
]}

机构：

[1] Univ Hosp Zurich, Div Gastroenterol & Hepatol, Ramistr 100, CH-8091 Zurich, Switzerland

[2] Univ Zurich, Div Clin Pharmacol & Toxicol, Zurich, Switzerland

[3] Univ Hosp Geneva, Swiss Pediat Liver Ctr, Geneva, Switzerland

[4] Univ Hosp Geneva, Div Clin Pathol, Diagnost Dept, Geneva, Switzerland

[5] Heinrich Heine Univ Dusseldorf, Dept Gastroenterol Hepatol & Infect Dis, Med Fac, Dusseldorf, Germany

来源：

LIVER INTERNATIONAL | 2019年 / 39卷 / 11期

关键词：

benign recurrent intrahepatic cholestasis; drug induced liver injury; RECURRENT INTRAHEPATIC CHOLESTASIS; GENETIC-DETERMINANTS; MUTATIONS; ABCB11; CHILDREN;

D O I：

10.1111/liv.14122

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report an unusual case of intermittent episodes of cholestasis in a young patient. The cholestatic attacks were preceded in each case by an infection and subsequent antibiotic therapies. After ruling out many possible causes of cholestatic hepatitis, the differential diagnoses were a benign recurrent intrahepatic cholestasis or a drug-induced liver injury. We discuss here the diagnostic approach and interpretation of the genetic analysis.

引用

页码：2036 / 2041

页数：6

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