Silver-Catalyzed Radical Tandem Cyclization for the Synthesis of 3,4-Disubstituted Dihydroquinolin-2(1H)-ones

被引：116
|
作者：
Mai, Wen-Peng [1 ]
Wang, Ji-Tao [1 ]
Yang, Liang-Ru [1 ]
Yuan, Jin-Wei [1 ]
Xiao, Yong-Mei [1 ]
Mao, Pu [1 ]
Qu, Ling-Bo [1 ]
机构：
[1] Henan Univ Technol, Chem & Chem Engn Sch, Zhengzhou 450001, Henan, Peoples R China
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 01期
关键词：
PLATELET AGGREGATION INHIBITORS; ALIPHATIC CARBOXYLIC-ACIDS; METAL-FREE SYNTHESIS; ACTIVATED ALKENES; 2-OXOQUINOLINE DERIVATIVES; OXIDATIVE TRIFLUOROMETHYLATION; H FUNCTIONALIZATION; OXINDOLE SYNTHESIS; ALPHA-ARYLATION; BOND;
D O I：
10.1021/ol403196h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A silver-catalyzed tandem decarboxylative radical addition/cyclization of N-arylcinnamamides with aliphatic carboxylic acids is reported. This method affords a novel and straightforward route to various 3,4-disubstituted dihydroquinolin-2(1H)-ones in aqueous solution.
引用
收藏
页码：204 / 207
页数：4
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