Omics approaches in food safety: fulfilling the promise?

被引:80
作者
Bergholz, Teresa M. [1 ]
Switt, Andrea I. Moreno [2 ]
Wiedmann, Martin [2 ]
机构
[1] N Dakota State Univ, Dept Vet & Microbiol Sci, Fargo, ND 58105 USA
[2] Cornell Univ, Dept Food Sci, Ithaca, NY 14853 USA
基金
美国国家卫生研究院; 美国食品与农业研究所;
关键词
genomics; transcriptomics; proteomics; synthetic biology; foodborne pathogens; food safety; FIELD GEL-ELECTROPHORESIS; LISTERIA-MONOCYTOGENES; BACILLUS-ANTHRACIS; UNITED-STATES; TRANSCRIPTIONAL RESPONSE; GENOME SEQUENCE; ACUTE DIARRHEA; SALMONELLA; OUTBREAK; STRAINS;
D O I
10.1016/j.tim.2014.01.006
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Genomics, transcriptomics, and proteomics are rapidly transforming our approaches to the detection, prevention, and treatment of foodborne pathogens. Microbial genome sequencing in particular has evolved from a research tool into an approach that can be used to characterize foodborne pathogen isolates as part of routine surveillance systems. Genome sequencing efforts will not only improve outbreak detection and source tracking, but will also create large amounts of foodborne pathogen genome sequence data, which will be available for data-mining efforts that could facilitate better source attribution and provide new insights into foodborne pathogen biology and transmission. Although practical uses and application of metagenomics, transcriptomics, and proteomics data and associated tools are less prominent, these tools are also starting to yield practical food safety solutions.
引用
收藏
页码:275 / 281
页数:7
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