Ontology driven integration platform for clinical and translational research

被引：14
|
作者：
Mirhaji, Parsa [1 ]
Zhu, Min [1 ]
Vagnoni, Mattew [1 ]
Bernstam, Elmer V. [1 ]
Zhang, Jiajie [1 ]
Smith, Jack W. [1 ]
机构：
[1] Univ Texas Houston, Hlth Sci Ctr, Houston, TX 77030 USA
来源：
BMC BIOINFORMATICS | 2009年 / 10卷
关键词：
Service Orient Architecture; Domain Ontology; Unify Medical Language System; Simple Knowledge Organization System; Clinical Text;
D O I：
10.1186/1471-2105-10-S2-S2
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Semantic Web technologies offer a promising framework for integration of disparate biomedical data. In this paper we present the semantic information integration platform under development at the Center for Clinical and Translational Sciences (CCTS) at the University of Texas Health Science Center at Houston (UTHSC-H) as part of our Clinical and Translational Science Award (CTSA) program. We utilize the Semantic Web technologies not only for integrating, repurposing and classification of multi-source clinical data, but also to construct a distributed environment for information sharing, and collaboration online. Service Oriented Architecture (SOA) is used to modularize and distribute reusable services in a dynamic and distributed environment. Components of the semantic solution and its overall architecture are described.
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页数：8
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