Advances in the Diagnosis and Therapeutic Management of Atopic Dermatitis

被引:12
|
作者
Vestergaard, Christian [1 ]
Deleuran, Mette [1 ]
机构
[1] Aarhus Univ Hosp, Dept Dermatol, DK-8000 Aarhus C, Denmark
关键词
DOWN-REGULATES FILAGGRIN; STAPHYLOCOCCUS-AUREUS COLONIZATION; ANTI-CD20 RITUXIMAB TREATMENT; COATED MYCOPHENOLATE SODIUM; INTERFERON-GAMMA-THERAPY; SKIN-BARRIER FUNCTION; LONG-TERM TREATMENT; DOUBLE-BLIND; TACROLIMUS OINTMENT; CYCLOSPORINE-A;
D O I
10.1007/s40265-014-0219-3
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Atopic dermatitis is a very prevalent disease that affects children as well as adults. The disease has a severe impact on quality of life for the patients and their families. The skin in atopic dermatitis patients is a site of both a severe inflammatory reaction dominated by lymphocytes and decreased skin barrier function. The treatment of the disease is mainly aimed at reducing the inflammation in the skin and/or restoring the skin barrier function. However, most of the treatments used today singularly aim at reducing the inflammation in the skin. Depending on the severity of the disease, the anti-inflammatory treatment may be topical or systemic, but basic treatment, no matter the severity, should always be emollients. In addition, new studies have shown good effects of psychosocial interventions, such as eczema schools, for patients and their families. This review covers the latest trends in the treatment of atopic dermatitis.
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页码:757 / 769
页数:13
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