Difference in Tracer Delay-induced Effect among Deconvolution Algorithms in CT Perfusion Analysis: Quantitative Evaluation with Digital Phantoms

被引：95

作者：

Kudo, Kohsuke ^{[1
]}

Sasaki, Makoto ^{[1
]}

Ogasawara, Kuniaki ^{[2
]}

Terae, Satoshi ^{[4
]}

Ehara, Shigeru ^{[3
]}

Shirato, Hiroki ^{[4
]}

机构：

[1] Iwate Med Univ, Adv Med Res Ctr, Morioka, Iwate 0208505, Japan

[2] Iwate Med Univ, Dept Neurosurg, Morioka, Iwate 0208505, Japan

[3] Iwate Med Univ, Dept Radiol, Morioka, Iwate 0208505, Japan

[4] Hokkaido Univ, Sch Med, Dept Radiol, Sapporo, Hokkaido 060, Japan

来源：

RADIOLOGY | 2009年 / 251卷 / 01期

关键词：

CEREBRAL-BLOOD-FLOW; SINGULAR-VALUE DECOMPOSITION; SUSCEPTIBILITY CONTRAST MRI; BOLUS DELAY; STROKE; DISPERSION; PARAMETERS; RESOLUTION; VOLUME;

D O I：

10.1148/radiol.2511080983

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Institutional review board approval and informed consent were obtained. The purpose was to evaluate the differences in tracer delay-induced effects of various deconvolution algorithms for computed tomographic (CT) perfusion imaging by using digital phantoms created from actual source data. Three methods of singular value decomposition (SVD) were evaluated. For standard SVD (sSVD), the delays induced significant errors in cerebral blood flow and mean transit time. In contrast, for block-circulant SVD (bSVD), these values remained virtually unchanged, whereas for delay-corrected SVD (dSVD), mild changes were observed. bSVD was superior to sSVD and dSVD for avoiding the tracer delay-induced effects in CT perfusion imaging. (C) RSNA, 2009

引用

页码：241 / 249

页数：9

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