Hemorrhage Rates and Risk Factors in the Natural History Course of Brain Arteriovenous Malformations

被引:92
作者
Rutledge, W. Caleb [1 ]
Ko, Nerissa U. [2 ]
Lawton, Michael T. [1 ]
Kim, Helen [3 ]
机构
[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94110 USA
[2] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94110 USA
[3] Univ Calif San Francisco, Dept Anesthesia & Perioperat Care, Ctr Cerebrovasc Res, San Francisco, CA 94110 USA
关键词
Arteriovenous malformation; Epidemiology; Intracerebral hemorrhage; Natural history; Risk factor; Survival; Treatment; TUMOR NECROSIS FACTOR-ALPHA-238G-GREATER-THAN-A; INTRACRANIAL HEMORRHAGE; SELECTING PATIENTS; LONGITUDINAL RISK; GENE; POLYMORPHISMS; ADULTS; INVOLVEMENT; POPULATION; EXPRESSION;
D O I
10.1007/s12975-014-0351-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Brain arteriovenous malformations (AVMs) are abnormal connections of arteries and veins, resulting in arteriovenous shunting of blood. Primary medical therapy is lacking; treatment options include surgery, radiosurgery, and embolization, often in combination. Judicious selection of AVM patients for treatment requires balancing risk of treatment complications against the risk of hemorrhage in the natural history course. This review focuses on the epidemiology, hemorrhage risk, and factors influencing risk of hemorrhage in the untreated natural course associated with sporadic brain AVM.
引用
收藏
页码:538 / 542
页数:5
相关论文
共 51 条
[1]   Association of tumor necrosis factor-α-238G>A and apolipoprotein E2 polymorphisms with intracranial hemorrhage after brain artericivenous malformation treatment [J].
Achrol, Achal S. ;
Kim, Helen ;
Pawlikowska, Ludmila ;
Poon, K. Y. Trudy ;
McCulloch, Charles E. ;
Ko, Nerissa U. ;
Johnston, S. Claiborne ;
McDermott, Michael W. ;
Zaroff, Jonathan G. ;
Lawton, Michael T. ;
Kwok, Pui-Yan ;
Young, William L. .
NEUROSURGERY, 2007, 61 (04) :731-739
[2]   Tumor necrosis factor-α-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations [J].
Achrol, AS ;
Pawlikowska, L ;
McCulloch, CE ;
Poon, KYT ;
Ha, C ;
Zaroff, JG ;
Johnston, SC ;
Lee, C ;
Lawton, MT ;
Sidney, S ;
Marchuk, DA ;
Kwok, PY ;
Young, WL .
STROKE, 2006, 37 (01) :231-234
[3]   Prospective, population-based detection of intracranial vascular malformations in adults - The Scottish Intracranial Vascular Malformation Study (SIVMS) [J].
Al-Shahi, R ;
Bhattacharya, JJ ;
Currie, DG ;
Papanastassiou, V ;
Ritchie, V ;
Roberts, RC ;
Sellar, RJ ;
Warlow, CP .
STROKE, 2003, 34 (05) :1163-1169
[4]   Prevalence of adults with brain arteriovenous malformations: a community based study in Scotland using capture-recapture analysis [J].
Al-Shahi, R ;
Fang, JSY ;
Lewis, SC ;
Warlow, CP .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2002, 73 (05) :547-551
[5]   The epidemiology of brain arteriovenous malformations [J].
Berman, MF ;
Sciacca, RR ;
Pile-Spellman, J ;
Stapf, C ;
Connolly, ES ;
Mohr, JP ;
Young, WL .
NEUROSURGERY, 2000, 47 (02) :389-+
[6]   THE NATURAL-HISTORY OF UNRUPTURED INTRACRANIAL ARTERIOVENOUS-MALFORMATIONS [J].
BROWN, RD ;
WIEBERS, DO ;
FORBES, G ;
OFALLON, WM ;
PIEPGRAS, DG ;
MARSH, WR ;
MACIUNAS, RJ .
JOURNAL OF NEUROSURGERY, 1988, 68 (03) :352-357
[7]   Molecular Imaging of Cerebrovascular Lesions [J].
Chalouhi, Nohra ;
Jabbour, Pascal ;
Magnotta, Vincent ;
Hasan, David .
TRANSLATIONAL STROKE RESEARCH, 2014, 5 (02) :260-268
[8]   Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1-deficient Brain [J].
Chen, Wanqiu ;
Guo, Yi ;
Walker, Espen J. ;
Shen, Fanxia ;
Jun, Kristine ;
Oh, S. Paul ;
Degos, Vincent ;
Lawton, Michael T. ;
Tihan, Tarik ;
Davalos, Dimitrios ;
Akassoglou, Katerina ;
Nelson, Jeffrey ;
Pile-Spellman, John ;
Su, Hua ;
Young, William L. .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2013, 33 (02) :305-+
[9]   Interleukin-6 involvement in brain arteriovenous malformations [J].
Chen, YM ;
Pawlikowska, L ;
Yao, JHS ;
Shen, FX ;
Zhai, WW ;
Achrol, AS ;
Lawton, MT ;
Kwok, PY ;
Yang, GY ;
Young, WL .
ANNALS OF NEUROLOGY, 2006, 59 (01) :72-80
[10]   Evidence of inflammatory cell involvement in brain arteriovenous malformations [J].
Chen, Yongmei ;
Zhu, Wei ;
Bollen, Andrew W. ;
Lawton, Michael T. ;
Barbaro, Nicholas M. ;
Dowd, Christopher F. ;
Hashimoto, Tomoki ;
Yang, Guo-Yuan ;
Young, William L. .
NEUROSURGERY, 2008, 62 (06) :1340-1349