Degradable polymer microspheres for controlled drug delivery

被引：0
|
作者：
Edlund, U [1 ]
Albertsson, AC [1 ]
机构：
[1] Royal Inst Technol, Dept Polymer Technol, S-10044 Stockholm, Sweden
来源：
DEGRADABLE ALIPHATIC POLYESTERS | 2002年 / 157卷
关键词：
controlled drug delivery; drug release; microspheres; degradation; erosion; polylactide; poly(glycolide-co-lactide); poly(epsilon-caprolactone); poly(hydroxyalkanoates); polyanhydrides; polycarbonates; poly(orthoesters); poly(1,5-dioxepan-2-one);
D O I：
暂无
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Controlled drug delivery technology is concerned with the systematic release of a pharmaceutical agent to maintain a therapeutic level of the drug in the body for a sustained period of time. This may be achieved by incorporating the therapeutic agent into a degradable polymer vehicle, releasing the agent continuously as the matrix erodes. This review is concerned with degradable polymers for use in controlled drug delivery with emphasis on the preparation, applications, biocompatibility, and stability of microspheres from hydrolytically degradable polymers.
引用
收藏
页码：67 / 112
页数：46
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