Severe polymorphic erythema due to interferon α-2b during treatment of hairy cell leukemia

被引：1
|
作者：
Li, Chen [1 ]
Geng, Hui [2 ]
Ji, Linhua [2 ]
Jiang, Yan [2 ]
Ma, Xiaojing [2 ]
Yin, Qichao [2 ]
Xiong, Hua [2 ]
机构：
[1] Qinghai Univ, Grad Sch, Xining, Qinghai, Peoples R China
[2] Qinghai Univ, Dept Haematol, Affiliated Hosp, 29 Tongren Rd, Xining 810000, Qinghai, Peoples R China
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2019年 / 47卷 / 07期
关键词：
Polymorphic erythema; interferon; hairy cell leukemia; blisters; skin biopsy; methylprednisolone; THERAPY; RASH;
D O I：
10.1177/0300060519856158
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A 54-year-old woman with hairy cell leukemia developed severe polymorphic erythema and blisters on the trunk and limbs after injection of interferon (IFN) alpha-2b. Skin biopsy revealed lymphocytic exocytosis and perivascular lymphocytic infiltrate in the dermis, and the lesions improved after methylprednisolone pulse therapy. Although injection-site reactions have been observed after injection of IFN alpha-2b, this is the first report of a widespread cutaneous reaction to IFN alpha-2b.
引用
收藏
页码：3453 / 3457
页数：5
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