Studying the membrane structure of chicken erythrocytes by in situ atomic force microscopy

被引:0
|
作者
Tian, Yongmei [1 ,2 ]
Cai, Mingjun [1 ]
Xu, Haijiao [1 ]
Wang, Hongda [1 ,2 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
基金
中国国家自然科学基金;
关键词
PROTEINS; CHOLESTEROL; MORPHOLOGY; RESOLUTION; EVENTS; PLASMA; RAFTS; AFM;
D O I
10.1039/c4ay01260g
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
High resolution atomic force microscopy and single molecule force spectroscopy revealed the asymmetric distribution of proteins on both sides of chicken erythrocyte membranes. The cholesterol-enriched domains were directly observed by in situ atomic force microscopy, providing the first direct evidence of lipid rafts in chicken erythrocyte membranes.
引用
收藏
页码:8115 / 8119
页数:5
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