Cultured salivary gland epithelial cells from patients with primary Sjogren's syndrome and disease controls are sensitive to signaling via Toll-like receptors 2 and 3: upregulation of intercellular adhesion molecule-1 expression

被引:1
|
作者
Spachidou, M. P. [1 ]
Kapsogeorgou, E. K. [1 ]
Bourazopoulou, E. A. [1 ]
Moutsopoulos, H. M. [1 ]
Manoussakis, M. N. [1 ]
机构
[1] Sch Med, Dept Pathophysiol, GR-10679 Athens, Greece
关键词
Peptidoglycan; Interferon Alpha; polyI; Minor Salivary Gland; TLR4 mRNA;
D O I
10.1186/ar1675
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S55 / S55
页数:1
相关论文
共 21 条
  • [1] Cultured salivary gland epithelial cells from patients with primary Sjögren's syndrome and disease controls are sensitive to signaling via Toll-like receptors 2 and 3: upregulation of intercellular adhesion molecule-1 expression
    MP Spachidou
    EK Kapsogeorgou
    EA Bourazopoulou
    HM Moutsopoulos
    MN Manoussakis
    Arthritis Research & Therapy, 7
  • [2] Expression of functional Toll-like receptors by salivary gland epithelial cells: increased mRNA expression in cells derived from patients with primary Sjogren's syndrome
    Spachidou, M. P.
    Bourazopoulou, E.
    Maratheftis, C. I.
    Kapsogeorgou, E. K.
    Moutsopoulos, H. M.
    Tzioufas, A. G.
    Manoussakis, M. N.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2007, 147 (03): : 497 - 503
  • [3] Activation of epithelial and myoepithelial cells in the salivary glands of patients with Sjogren's syndrome: high expression of intercellular adhesion molecule-1 (ICAM.1) in biopsy specimens and cultured cells
    Kapsogeorgou, EK
    Dimitriou, ID
    Abu-Helu, RF
    Moutsopoulos, HM
    Manoussakis, MN
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2001, 124 (01): : 126 - 133
  • [4] Functional toll-like receptors (TLRs) are expressed by cultured salivary gland epithelial cells: Increased mRNA expression of TLR-1,-2 and-4 in cells derived from patients with primary Sjogren syndrome.
    Spachidou, MP
    Bourazopoulou, E
    Kapsogeorgou, EK
    Maratheftis, CI
    Moutsopoulos, HM
    Tzioufas, AG
    Manoussakis, MN
    ARTHRITIS AND RHEUMATISM, 2005, 52 (09): : S278 - S278
  • [5] Vasculitis and expression of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and E-selectin in salivary glands of patients with Sjogren's syndrome
    Turkcapar, N
    Sak, SD
    Saatci, M
    Duman, M
    Olmez, U
    JOURNAL OF RHEUMATOLOGY, 2005, 32 (06) : 1063 - 1070
  • [6] Expression of Toll-Like Receptors in Peripheral Blood Mononuclear Cells of Patients with Primary Sjogren's Syndrome
    Karlsen, M.
    Jakobsen, K.
    Jonsson, R.
    Hammenfors, D.
    Hansen, T.
    Appel, S.
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2017, 85 (03) : 220 - 226
  • [7] Expression of the chemokine receptor CXCR3 by salivary gland epithelial cells in patients with Sjogren's syndrome, healthy controls and in a human parotid gland cell line
    Sfriso, P
    Oliviero, F
    Miorin, M
    Baesso, I
    Calabrese, F
    Grava, C
    Botsios, C
    Ostuni, P
    Todesco, S
    Agostini, C
    Punzi, L
    ANNALS OF THE RHEUMATIC DISEASES, 2004, 63 : 353 - 354
  • [8] CD40 on salivary gland epithelial cells: high constitutive expression by cultured cells from Sjogren's syndrome patients indicating their intrinsic activation
    Dimitriou, ID
    Kapsogeorgou, EK
    Moutsopoulos, HM
    Manoussakis, MN
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2002, 127 (02): : 386 - 392
  • [9] THE EXPRESSION OF THE TRANSCRIPTION FACTOR PPAR-GAMMA IS SIGNIFICANTLY REDUCED IN THE SALIVARY GLAND EPITHELIAL CELLS FROM PATIENTS WITH PRIMARY SJOGREN'S SYNDROME
    Vakrakou, Aigli G.
    Gourzi, Vicky
    Kapsogeorgou, Efstathia
    Manoussakis, Menelaos N.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : A11 - A11
  • [10] Toll-like receptor-3 triggering of salivary gland epithelial cells (SGEC) causes detachment-induced cell death (anoikia) that is more pronounced in cells derived from Sjogren's syndrome patients
    Spachidou, M. P.
    Kapsogeorgou, E. K.
    Moutsopoulos, H. M.
    Manoussakis, M. N.
    ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 : A36 - A36