Alantolactone, a sesquiterpene lactone isolated from Inula helenium L. selectively suppresses STAT3 activation and exhibits anticancer activity in MDA-MB-231 cells

被引：0
|
作者：
Chun, J. [1 ]
Kim, Y. S. [1 ]
机构：
[1] Seoul Natl Univ, Coll Pharm, Inst Nat Prod Res, Seoul, South Korea
来源：
PLANTA MEDICA | 2015年 / 81卷 / 16期
关键词：
D O I：
暂无
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
PM-11
引用
收藏
页码：1426 / 1426
页数：1
相关论文
共 20 条
  • [1] Alantolactone selectively suppresses STAT3 activation and exhibits potent anticancer activity in MDA-MB-231 cells
    Chun, Jaemoo
    Li, Rui-Juan
    Cheng, Mao-Sheng
    Kim, Yeong Shik
    CANCER LETTERS, 2015, 357 (01) : 393 - 403
  • [2] A Piscibacillus sp. Isolated from A Soda Lake Exhibits Anticancer Activity Against Breast Cancer MDA-MB-231 Cells
    Neelam, Deepesh Kumar
    Agrawal, Akhil
    Tomer, Anuj Kumar
    Bandyopadhayaya, Shreetama
    Sharma, Ankit
    Jagannadham, Medicharla, V
    Mandal, Chandi C.
    Dadheech, Pawan K.
    MICROORGANISMS, 2019, 7 (02):
  • [3] Sesquiterpene lactones-enriched fraction of Inula helenium L. induces apoptosis through inhibition of signal transducers and activators of transcription 3 signaling pathway in MDA-MB-231 breast cancer cells
    Chun, Jaemoo
    Song, Kwangho
    Kim, Yeong Shik
    PHYTOTHERAPY RESEARCH, 2018, 32 (12) : 2501 - 2509
  • [4] The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells
    Yong-Jin Kwon
    Eun-Bi Seo
    Ae Jin Jeong
    Song-Hee Lee
    Kum Hee Noh
    Sangsik Lee
    Chung-Hyun Cho
    Chang-Han Lee
    Hyun Mu Shin
    Hang-Rae Kim
    Hyeong-Gon Moon
    Sang-Kyu Ye
    BMC Cancer, 22
  • [5] The acidic tumor microenvironment enhances PD-L1 expression via activation of STAT3 in MDA-MB-231 breast cancer cells
    Kwon, Yong-Jin
    Seo, Eun-Bi
    Jeong, Ae Jin
    Lee, Song-Hee
    Noh, Kum Hee
    Lee, Sangsik
    Cho, Chung-Hyun
    Lee, Chang-Han
    Shin, Hyun Mu
    Kim, Hang-Rae
    Moon, Hyeong-Gon
    Ye, Sang-Kyu
    BMC CANCER, 2022, 22 (01)
  • [6] Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells
    Sapio, Luigi
    Sorvillo, Luca
    Illiano, Michela
    Chiosi, Emilio
    Spina, Annamaria
    Naviglio, Silvio
    MOLECULES, 2015, 20 (09) : 15910 - 15928
  • [7] Ethyl acetate extract from Inula helenium L. inhibits the proliferation of pancreatic cancer cells by regulating the STAT3/AKT pathway
    Zhang, Bo
    Zeng, Jianmei
    Yan, Youyou
    Yang, Bo
    Huang, Mincong
    Wang, Linling
    Zhang, Qi
    Lin, Nengming
    MOLECULAR MEDICINE REPORTS, 2018, 17 (04) : 5440 - 5448
  • [8] Igalan from Inula helenium (L.) suppresses the atopic dermatitis-like response in stimulated HaCaT keratinocytes via JAK/STAT3 signaling
    Thien T. P. Dao
    Kwangho Song
    Jee Young Kim
    Yeong Shik Kim
    Inflammation Research, 2020, 69 : 309 - 319
  • [9] Igalan from Inula helenium (L.) suppresses the atopic dermatitis-like response in stimulated HaCaT keratinocytes via JAK/STAT3 signaling
    Dao, Thien T. P.
    Song, Kwangho
    Kim, Jee Young
    Kim, Yeong Shik
    INFLAMMATION RESEARCH, 2020, 69 (03) : 309 - 319
  • [10] Isolation and anticancer activity of quercetin from Acalypha indica L. against breast cancer cell lines MCF-7 and MDA-MB-231
    Sudhakar Chekuri
    Satyanarayana Swamy Vyshnava
    Swarupa Lakshmi Somisetti
    Sai Bindu Karamthote Cheniya
    Chakradhar Gandu
    Roja Rani Anupalli
    3 Biotech, 2023, 13
12