Role of Integrins in cellular responses to mechanical stress

被引：0

作者：

Zhang, HJ ^{[1
]}

Cai, SX ^{[1
]}

Lu, X ^{[1
]}

机构：

[1] Chongqing Univ, Bioengn Inst, Chongqing 400044, Peoples R China

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2002年 / 29卷 / 03期

关键词：

integrin; mechanical stress; extracellular matrices (ECM); mechanotransduction;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mechanical stresses play critical roles in normal cellular functions and pathophysiological processes. Integrins, which are transmembrane molecules that interact with both extracellular matrices and intercellular cytoskeleton and kinases in the focal adhesion, are important in mechanotransduction. There is increasing evidence that the dynamic and specific interaction between integrin and extracellular matrices is essential for mechanotransduction.

引用

页码：359 / 362

页数：4

共 18 条

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