Non-uniformity of binder distribution in high-shear granulation

被引：39
|
作者：
Reynolds, GK [1 ]
Biggs, CA [1 ]
Salman, AD [1 ]
Hounslow, MJ [1 ]
机构：
[1] Univ Sheffield, Dept Chem & Proc Engn, Sheffield S1 3JD, S Yorkshire, England
来源：
POWDER TECHNOLOGY | 2004年 / 140卷 / 03期
关键词：
non-uniformity; binder distribution; high-shear granulation;
D O I：
10.1016/j.powtec.2004.01.017
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Further experimental investigation based on a microscopic, or single granule, scale has been conducted to investigate the uniformity of binder composition within a given size class for high shear melt granulation. This work assesses whether there is significant non-uniformity of binder composition within size classes to warrant considering this level of detail to improving population balance modelling of high shear granulation. It is concluded that at early times in a batch granulation process there is a broad variation in binder content between individual granules and that this variation persists in granules of small size. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：203 / 208
页数：6
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