A facile and practical one-pot 'catch and release' synthesis of substituted guanidines

被引：13

作者：

Wang, Ying ^{[1
]}

Sauer, Daryl R. ^{[1
]}

Djuric, Stevan W. ^{[1
]}

机构：

[1] Abbott Labs, High Throughput Organ Synth Grp, Abbott Pk, IL 60064 USA

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 36期

关键词：

SOLID-PHASE SYNTHESIS; COMBINATORIAL SYNTHESIS; STRATEGY;

D O I：

10.1016/j.tetlet.2009.06.113

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A 'catch and release' two-step one-pot protocol has been developed for the facile and practical synthesis of substituted guanidines from thioureas and various amines utilizing readily available brominated polystyrene resin. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：5145 / 5148

页数：4

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